Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   PQ615_RS05235 Genome accession   NZ_CP117058
Coordinates   1090803..1092032 (+) Length   409 a.a.
NCBI ID   WP_003099812.1    Uniprot ID   -
Organism   Streptococcus iniae strain LSSM211007SI     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1089163..1111391 1090803..1092032 within 0


Gene organization within MGE regions


Location: 1089163..1111391
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PQ615_RS05225 (PQ615_05225) - 1089163..1090002 (+) 840 WP_017794807.1 thymidylate synthase -
  PQ615_RS05230 (PQ615_05230) - 1090081..1090578 (+) 498 WP_003099817.1 dihydrofolate reductase -
  PQ615_RS05235 (PQ615_05235) clpX 1090803..1092032 (+) 1230 WP_003099812.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  PQ615_RS05240 (PQ615_05240) yihA 1092042..1092641 (+) 600 WP_003099810.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  PQ615_RS05245 (PQ615_05245) - 1092749..1093462 (+) 714 WP_003099809.1 hypothetical protein -
  PQ615_RS05250 (PQ615_05250) - 1093534..1094876 (+) 1343 Protein_1023 IS3 family transposase -
  PQ615_RS05255 (PQ615_05255) - 1095022..1095975 (+) 954 WP_003098612.1 IS30 family transposase -
  PQ615_RS05260 (PQ615_05260) rplJ 1096239..1096739 (+) 501 WP_003099802.1 50S ribosomal protein L10 -
  PQ615_RS05265 (PQ615_05265) rplL 1096803..1097168 (+) 366 WP_003099800.1 50S ribosomal protein L7/L12 -
  PQ615_RS05270 (PQ615_05270) tnpA 1097391..1097831 (+) 441 WP_003099798.1 IS200/IS605 family transposase -
  PQ615_RS05275 (PQ615_05275) - 1097899..1099004 (+) 1106 WP_089180059.1 IS3 family transposase -
  PQ615_RS05280 (PQ615_05280) - 1099349..1100524 (-) 1176 WP_003099056.1 IS256 family transposase -
  PQ615_RS05285 (PQ615_05285) - 1100784..1101704 (-) 921 WP_003099793.1 polysaccharide deacetylase family protein -
  PQ615_RS05290 (PQ615_05290) - 1101889..1103175 (+) 1287 WP_003099788.1 homoserine dehydrogenase -
  PQ615_RS05295 (PQ615_05295) thrB 1103177..1104037 (+) 861 WP_003099786.1 homoserine kinase -
  PQ615_RS05300 (PQ615_05300) - 1104121..1105380 (+) 1260 WP_003099784.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  PQ615_RS05305 (PQ615_05305) folE 1105409..1105972 (+) 564 WP_003099782.1 GTP cyclohydrolase I FolE -
  PQ615_RS05310 (PQ615_05310) folP 1105982..1106782 (+) 801 WP_003099781.1 dihydropteroate synthase -
  PQ615_RS05315 (PQ615_05315) folB 1106789..1107148 (+) 360 WP_003099779.1 dihydroneopterin aldolase -
  PQ615_RS05320 (PQ615_05320) folK 1107145..1107636 (+) 492 WP_003099778.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  PQ615_RS05325 (PQ615_05325) - 1107888..1109054 (-) 1167 WP_003099776.1 IS30 family transposase -
  PQ615_RS05330 (PQ615_05330) murB 1109309..1110202 (+) 894 WP_003099774.1 UDP-N-acetylmuramate dehydrogenase -
  PQ615_RS05335 (PQ615_05335) - 1110237..1111391 (+) 1155 WP_003099772.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45151.78 Da        Isoelectric Point: 4.4847

>NTDB_id=782447 PQ615_RS05235 WP_003099812.1 1090803..1092032(+) (clpX) [Streptococcus iniae strain LSSM211007SI]
MAVNRTNDIKVHCSFCGKDQDEVKKIIAGNNVFICDECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVVGQDH
AKKALAVAVYNHYKRVSFTESRDEDEVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTEASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDEDASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLTVADLIQI
LTEPRNALVKQYQALLSYDGVELEFEKAALEAIAAKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVIKVRITKDSVDG
LKKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=782447 PQ615_RS05235 WP_003099812.1 1090803..1092032(+) (clpX) [Streptococcus iniae strain LSSM211007SI]
ATGGCAGTTAATCGTACAAACGATATTAAGGTCCATTGTTCATTTTGTGGCAAGGACCAAGATGAAGTTAAAAAAATTAT
TGCAGGGAACAATGTTTTCATCTGTGATGAATGTGTTGCATTATCTCAAGAAATTATAAAAGAAGAATTAGCAGAGGAAG
TATTAGCTGATTTAACGGAAGTTCCAAAACCAAAAGAACTTTTAGATATTTTAAATCAATATGTTGTTGGTCAAGACCAT
GCTAAAAAGGCTTTAGCAGTAGCAGTTTATAACCATTATAAGCGTGTTTCGTTTACAGAAAGTCGCGATGAAGATGAAGT
GGAATTGCAAAAGTCAAATATTCTCATGATTGGCCCAACTGGTTCAGGAAAAACCTTCTTGGCACAAACTTTGGCAAAAA
GTTTAAATGTACCATTTGCCATTGCGGATGCTACTTCATTAACTGAAGCTGGCTATGTCGGCGAAGATGTTGAGAATATT
CTGCTAAAATTAATTCAAGCAGCTGATTATAATGTAGAACGTGCAGAACGTGGCATTATTTATGTTGATGAAATTGATAA
AATTGCTAAAAAAGGGGAAAATGTTTCCATTACACGCGATGTCTCTGGTGAAGGTGTTCAACAAGCCCTGCTAAAAATTA
TTGAAGGCACAGAAGCAAGTGTTCCACCTCAAGGTGGACGTAAACACCCTAATCAAGAGATGATTCAAATTGATACGAAA
AATATTTTGTTCATCGTTGGTGGCGCTTTTGATGGCATTGAAGAAATTGTTAAACAGCGTCTTGGAGAAAAAATTATTGG
TTTTGGCCAAAATAGCCGTAAAATTGATGAAGATGCTTCATATATGCAAGAAATTATCGCAGAAGACATTCAAAAATTTG
GCCTTATTCCAGAATTTATTGGACGCTTACCTGTTGTTGCAGCCTTAGAACAGTTAACAGTTGCTGACCTGATTCAAATT
TTAACAGAACCAAGAAATGCTCTTGTTAAACAATACCAAGCTCTTTTATCTTATGATGGTGTTGAACTTGAATTTGAAAA
GGCTGCTTTGGAAGCTATTGCTGCAAAAGCTATAGAACGTAAAACTGGTGCGCGTGGCCTTCGTTCAATCATTGAAGAAA
CCATGCTTGACATTATGTTTGAAATCCCTAGTCAAGAAGATGTTATTAAGGTTCGCATTACTAAGGACTCTGTGGATGGG
CTTAAAAAACCTATTTTGGAAACGGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.775

100

0.878
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.895

97.555

0.565