Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PO908_RS07510 Genome accession   NZ_CP117042
Coordinates   1448310..1448999 (-) Length   229 a.a.
NCBI ID   WP_021001982.1    Uniprot ID   A0A1S1F9U0
Organism   Streptococcus anginosus strain CGMH_KH1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1443310..1453999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PO908_RS07490 (PO908_07465) nrdR 1443795..1444268 (-) 474 WP_003023591.1 transcriptional regulator NrdR -
  PO908_RS07495 (PO908_07470) - 1444434..1445030 (+) 597 WP_021001979.1 hypothetical protein -
  PO908_RS07500 (PO908_07475) - 1445077..1445892 (-) 816 WP_021001980.1 endonuclease/exonuclease/phosphatase family protein -
  PO908_RS07505 (PO908_07480) - 1445909..1448098 (-) 2190 WP_021001981.1 PTS transporter subunit IIBC -
  PO908_RS07510 (PO908_07485) covR 1448310..1448999 (-) 690 WP_021001982.1 response regulator transcription factor Regulator
  PO908_RS07515 (PO908_07490) gndA 1449008..1450432 (-) 1425 WP_021001983.1 NADP-dependent phosphogluconate dehydrogenase -
  PO908_RS07520 (PO908_07495) - 1450731..1451354 (-) 624 WP_003023578.1 DNA alkylation repair protein -
  PO908_RS07525 (PO908_07500) - 1451405..1451941 (-) 537 WP_021001984.1 DUF177 domain-containing protein -
  PO908_RS07530 (PO908_07505) - 1452106..1452786 (+) 681 WP_373878980.1 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26472.55 Da        Isoelectric Point: 6.2732

>NTDB_id=782260 PO908_RS07510 WP_021001982.1 1448310..1448999(-) (covR) [Streptococcus anginosus strain CGMH_KH1]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=782260 PO908_RS07510 WP_021001982.1 1448310..1448999(-) (covR) [Streptococcus anginosus strain CGMH_KH1]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAATTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S1F9U0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

100

0.454