Detailed information NTG0780194

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QYT30_RS01555
• Genome accession: NZ_CP129557
• Coordinates: 287760..288803 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: Q99SZ7
• Organism: Staphylococcus aureus strain 46D
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 282760..293803

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QYT30_RS01525 (QYT30_01530)	-	283485..283595 (+)	111	WP_014937049.1	hypothetical protein	-
QYT30_RS01530 (QYT30_01535)	-	283624..284037 (+)	414	WP_025174370.1	hypothetical protein	-
QYT30_RS01535 (QYT30_01540)	-	284226..285212 (-)	987	WP_000999712.1	FUSC family protein	-
QYT30_RS01540 (QYT30_01545)	map	285686..286444 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
QYT30_RS01545 (QYT30_01550)	-	286661..287047 (+)	387	WP_001110182.1	hypothetical protein	-
QYT30_RS01550 (QYT30_01555)	liaF	287062..287763 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QYT30_RS01555 (QYT30_01560)	vraS	287760..288803 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QYT30_RS01560 (QYT30_01565)	vraR	288793..289422 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QYT30_RS01565 (QYT30_01570)	-	289535..290752 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
QYT30_RS01570 (QYT30_01575)	-	291030..291305 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
QYT30_RS01575 (QYT30_01580)	-	291312..291776 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QYT30_RS01580 (QYT30_01585)	-	291923..292123 (+)	201	WP_000180460.1	DUF1128 family protein	-
QYT30_RS01585 (QYT30_01590)	-	292126..293382 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=780194 QYT30_RS01555 WP_001017131.1 287760..288803(+) (vraS) [Staphylococcus aureus strain 46D]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=780194 QYT30_RS01555 WP_001017131.1 287760..288803(+) (vraS) [Staphylococcus aureus strain 46D]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q99SZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1