Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   PND17_RS00305 Genome accession   NZ_CP116772
Coordinates   56888..58114 (+) Length   408 a.a.
NCBI ID   WP_116920144.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain strain TSGB 4141     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 51888..63114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PND17_RS00280 (PND17_00280) - 52463..53734 (-) 1272 WP_271298094.1 hydroxymethylglutaryl-CoA reductase, degradative -
  PND17_RS00285 (PND17_00285) - 53727..54902 (-) 1176 WP_084829447.1 hydroxymethylglutaryl-CoA synthase -
  PND17_RS00290 (PND17_00290) - 55224..56084 (+) 861 WP_002950145.1 thymidylate synthase -
  PND17_RS00295 (PND17_00295) - 56192..56695 (+) 504 WP_271298093.1 dihydrofolate reductase -
  PND17_RS00300 (PND17_00300) - 56700..56870 (+) 171 WP_271298092.1 hypothetical protein -
  PND17_RS00305 (PND17_00305) clpX 56888..58114 (+) 1227 WP_116920144.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  PND17_RS00310 (PND17_00310) yihA 58124..58723 (+) 600 WP_002950154.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  PND17_RS00315 (PND17_00315) - 58853..60229 (+) 1377 WP_014608109.1 amino acid permease -
  PND17_RS00320 (PND17_00320) mmuM 60241..61191 (+) 951 WP_233002200.1 homocysteine S-methyltransferase -
  PND17_RS00325 (PND17_00325) - 61304..61558 (+) 255 WP_002950164.1 DUF1912 family protein -
  PND17_RS00330 (PND17_00330) - 61630..61989 (+) 360 WP_271298091.1 helix-hairpin-helix domain-containing protein -
  PND17_RS00335 (PND17_00335) plsY 62103..62744 (-) 642 WP_002950167.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45051.50 Da        Isoelectric Point: 4.4119

>NTDB_id=780019 PND17_RS00305 WP_116920144.1 56888..58114(+) (clpX) [Streptococcus thermophilus strain strain TSGB 4141]
MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRV
KRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKN
ILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSMEDVTKVRITKEAVDGK
AAPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=780019 PND17_RS00305 WP_116920144.1 56888..58114(+) (clpX) [Streptococcus thermophilus strain strain TSGB 4141]
ATGGCTGGAAATCGTAATGAAGAGATGGTTTATTGTTCATTTTGTGGCAAAAACCAAGAAGAAGTGAAGAAAATTATCGC
CGGTAATGGCGTCTTTATCTGTAACGAATGTGTGGCCTTGTCACAAGAAATCATTCGTGAGGAAACGGCTGAAGAAGTTT
TAGCTGACTTGGCTGAAACGCCAAAGCCAAAAGAACTTTTAGATATTTTGAACAACTATGTCGTGGGGCAAGATCGTGTC
AAACGTGCCTTGGCAGTAGCTGTTTACAACCACTATAAACGTATCAACTTCACAGAAAGTCGTGAAGATAATGATGTGGA
CTTGCAAAAATCAAATATCCTCATGATTGGACCAACAGGGTCAGGGAAAACTTACTTAGCTCAGACTTTGGCTCGTAGTT
TGAATGTTCCTTTCGCGATTGCGGATGCGACATCATTGACAGAGGCAGGTTATGTGGGTGAGGATGTGGAAAATATCCTC
CTCAAACTAATCCAAGCGGCAGACTTTAATATTGAACGTGCGGAACGTGGGATTATCTACGTGGACGAGATTGATAAGAT
TGCCAAAAAAGGTGAGAATGTTTCAATCACTCGTGATGTTTCAGGTGAAGGGGTTCAACAAGCTCTCTTGAAGATTATTG
AGGGAACAGTGGCTAGTGTTCCACCTCAAGGTGGTCGTAAACACCCTAATCAAGAGATGATTCAAATTGATACTAAGAAT
ATTCTCTTTATCGTGGGTGGTGCTTTTGATGGTATCGAAGATATCGTTAAGCAACGTCTTGGTGAGAAAATCATTGGGTT
TGGTCAAAATAATAAAGCAATTGATGACGAATCATCATACATGAAAGAAATTGTGGCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTGCCAGTTCTCGCGGCCCTTGAACAGTTAACGGTTGACGACTTGGTGCGTATTTTG
ACAGAGCCTAGGAATGCCTTGGTGAAGCAGTATCAAACCCTCTTGTCTTATGATGGGGTTGAACTTGAGTTTGACCAGGA
TGCCCTTGAGGCTATTGCAAGTAAGGCAATTGAACGTAAGACTGGTGCGCGTGGGCTTCGCTCTATCATTGAAGAAGTCA
TGATGGATGTTATGTTTGAAATCCCTAGTATGGAAGATGTCACTAAGGTTCGTATCACCAAAGAAGCTGTTGATGGGAAA
GCTGCTCCAGTATTGGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

88.753

100

0.89
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.757

99.755

0.566