Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   QYM42_RS12325 Genome accession   NZ_CP129526
Coordinates   2456562..2458532 (-) Length   656 a.a.
NCBI ID   WP_032947013.1    Uniprot ID   -
Organism   Lactococcus lactis strain ZZ-2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2451562..2463532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QYM42_RS12300 (QYM42_12300) - 2451946..2453133 (-) 1188 WP_251899986.1 ABC transporter permease -
  QYM42_RS12305 (QYM42_12305) - 2453200..2453490 (-) 291 WP_251899987.1 hypothetical protein -
  QYM42_RS12310 (QYM42_12310) - 2453710..2454594 (-) 885 WP_012898698.1 XRE/MutR family transcriptional regulator -
  QYM42_RS12315 (QYM42_12315) ruvB 2454731..2455732 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  QYM42_RS12320 (QYM42_12320) ruvA 2455859..2456452 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  QYM42_RS12325 (QYM42_12325) hexB 2456562..2458532 (-) 1971 WP_032947013.1 DNA mismatch repair endonuclease MutL Machinery gene
  QYM42_RS12330 (QYM42_12330) - 2458661..2459356 (-) 696 WP_012898700.1 hypothetical protein -
  QYM42_RS12335 (QYM42_12335) hexA 2459471..2461993 (-) 2523 WP_301675297.1 DNA mismatch repair protein MutS Machinery gene
  QYM42_RS12340 (QYM42_12340) - 2462187..2462534 (-) 348 WP_012898702.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73773.01 Da        Isoelectric Point: 5.1824

>NTDB_id=779757 QYM42_RS12325 WP_032947013.1 2456562..2458532(-) (hexB) [Lactococcus lactis strain ZZ-2]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTVEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKEALSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQPSNDSSEQTFDNFTE
NQLNTDAVNEKITDRTVESTTEITDNSLENTVSNFEIDFDNEAKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=779757 QYM42_RS12325 WP_032947013.1 2456562..2458532(-) (hexB) [Lactococcus lactis strain ZZ-2]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGGT
TAATTGAAGTTATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTTGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGTTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGTTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
AGCTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAGCCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAATGAAAAAATTACTGACAGAACTGTTGAAAGTACAACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGCAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATAAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGTAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAGTCAGCTAGAGCATTGCTTGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-123)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(455-598)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.836

99.238

0.564