Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PHA78_RS09500 Genome accession   NZ_CP116604
Coordinates   1950924..1951613 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus sp. HN38     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1945924..1956613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA78_RS09475 - 1946013..1946726 (-) 714 WP_099877837.1 nitroreductase family protein -
  PHA78_RS09480 dnaI 1946723..1947622 (-) 900 WP_002942703.1 primosomal protein DnaI -
  PHA78_RS09485 - 1947622..1948773 (-) 1152 WP_024378531.1 replication initiation/membrane attachment protein -
  PHA78_RS09490 nrdR 1948760..1949251 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  PHA78_RS09495 - 1949323..1950453 (-) 1131 WP_002942701.1 AI-2E family transporter -
  PHA78_RS09500 covR 1950924..1951613 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  PHA78_RS09505 gndA 1951695..1953122 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  PHA78_RS09510 - 1953210..1953749 (-) 540 WP_029176115.1 DUF177 domain-containing protein -
  PHA78_RS09515 trxB 1953759..1954676 (-) 918 WP_029176114.1 thioredoxin-disulfide reductase -
  PHA78_RS09520 - 1954690..1954914 (-) 225 WP_002936682.1 DUF4059 family protein -
  PHA78_RS09525 - 1954932..1956275 (-) 1344 WP_002936685.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=778782 PHA78_RS09500 WP_012027645.1 1950924..1951613(-) (covR) [Streptococcus sp. HN38]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=778782 PHA78_RS09500 WP_012027645.1 1950924..1951613(-) (covR) [Streptococcus sp. HN38]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGATAATAATTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432