Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   PFZ59_RS06040 Genome accession   NZ_CP116393
Coordinates   1180298..1180987 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain SS/UPM/MY/F001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1175298..1185987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PFZ59_RS06015 (PFZ59_06015) - 1175627..1176970 (+) 1344 WP_024384547.1 DEAD/DEAH box helicase -
  PFZ59_RS06020 (PFZ59_06020) - 1176988..1177212 (+) 225 WP_002936682.1 DUF4059 family protein -
  PFZ59_RS06025 (PFZ59_06025) trxB 1177226..1178143 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  PFZ59_RS06030 (PFZ59_06030) - 1178153..1178692 (+) 540 WP_024385904.1 DUF177 domain-containing protein -
  PFZ59_RS06035 (PFZ59_06035) gndA 1178789..1180216 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  PFZ59_RS06040 (PFZ59_06040) covR 1180298..1180987 (+) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  PFZ59_RS06045 (PFZ59_06045) - 1181077..1182207 (+) 1131 WP_277697727.1 AI-2E family transporter -
  PFZ59_RS06050 (PFZ59_06050) nrdR 1182279..1182770 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  PFZ59_RS06055 (PFZ59_06055) - 1182757..1183908 (+) 1152 WP_277697728.1 replication initiation/membrane attachment protein -
  PFZ59_RS06060 (PFZ59_06060) dnaI 1183908..1184807 (+) 900 WP_002938337.1 primosomal protein DnaI -
  PFZ59_RS06065 (PFZ59_06065) - 1184804..1185517 (+) 714 WP_208580864.1 NADPH-dependent oxidoreductase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=777096 PFZ59_RS06040 WP_012027645.1 1180298..1180987(+) (covR) [Streptococcus suis strain SS/UPM/MY/F001]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=777096 PFZ59_RS06040 WP_012027645.1 1180298..1180987(+) (covR) [Streptococcus suis strain SS/UPM/MY/F001]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCTACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACTCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432