Detailed information
Bioinformatically predicted
Overview
| Name | htrA | Type | Regulator |
| Locus tag | PFZ59_RS02990 | Genome accession | NZ_CP116393 |
| Coordinates | 566650..567846 (+) | Length | 398 a.a. |
| NCBI ID | WP_024384306.1 | Uniprot ID | A0A2S2F7U7 |
| Organism | Streptococcus suis strain SS/UPM/MY/F001 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 537015..573186 | 566650..567846 | within | 0 |
Gene organization within MGE regions
Location: 537015..573186
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PFZ59_RS02800 (PFZ59_02800) | - | 537015..537575 (-) | 561 | WP_208581348.1 | LysM domain-containing protein | - |
| PFZ59_RS02805 (PFZ59_02805) | - | 537707..538501 (-) | 795 | WP_208581346.1 | energy-coupling factor transporter transmembrane protein EcfT | - |
| PFZ59_RS02810 (PFZ59_02810) | - | 538494..539336 (-) | 843 | WP_208581344.1 | energy-coupling factor transporter ATPase | - |
| PFZ59_RS02815 (PFZ59_02815) | - | 539312..540148 (-) | 837 | WP_208581367.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
| PFZ59_RS02820 (PFZ59_02820) | pgsA | 540148..540687 (-) | 540 | WP_014638849.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| PFZ59_RS02825 (PFZ59_02825) | rodZ | 540707..541561 (-) | 855 | WP_105256919.1 | cytoskeleton protein RodZ | - |
| PFZ59_RS02830 (PFZ59_02830) | - | 541643..542926 (-) | 1284 | WP_014638851.1 | pitrilysin family protein | - |
| PFZ59_RS02835 (PFZ59_02835) | - | 542923..544176 (-) | 1254 | WP_208581342.1 | pitrilysin family protein | - |
| PFZ59_RS02840 (PFZ59_02840) | - | 544498..544683 (-) | 186 | WP_277697439.1 | hypothetical protein | - |
| PFZ59_RS02845 (PFZ59_02845) | - | 544670..545047 (-) | 378 | WP_277697440.1 | replication protein | - |
| PFZ59_RS02850 (PFZ59_02850) | - | 545054..545710 (-) | 657 | WP_277697441.1 | hypothetical protein | - |
| PFZ59_RS02855 (PFZ59_02855) | - | 545789..545935 (-) | 147 | WP_277697442.1 | hypothetical protein | - |
| PFZ59_RS02860 (PFZ59_02860) | - | 545926..546399 (-) | 474 | WP_277697443.1 | hypothetical protein | - |
| PFZ59_RS02865 (PFZ59_02865) | - | 546412..547215 (-) | 804 | WP_277697444.1 | DnaD domain protein | - |
| PFZ59_RS02870 (PFZ59_02870) | - | 547202..547486 (-) | 285 | WP_277697445.1 | XRE family transcriptional regulator | - |
| PFZ59_RS02875 (PFZ59_02875) | - | 547476..547814 (-) | 339 | WP_277697446.1 | hypothetical protein | - |
| PFZ59_RS02880 (PFZ59_02880) | - | 547826..548029 (-) | 204 | WP_347176375.1 | hypothetical protein | - |
| PFZ59_RS02885 (PFZ59_02885) | - | 548031..548474 (-) | 444 | WP_277697448.1 | hypothetical protein | - |
| PFZ59_RS02890 (PFZ59_02890) | - | 548755..548925 (-) | 171 | WP_277697449.1 | hypothetical protein | - |
| PFZ59_RS02895 (PFZ59_02895) | - | 549405..550043 (-) | 639 | WP_277697450.1 | Rha family transcriptional regulator | - |
| PFZ59_RS02900 (PFZ59_02900) | - | 550054..550749 (-) | 696 | WP_277697451.1 | Rha family transcriptional regulator | - |
| PFZ59_RS02905 (PFZ59_02905) | - | 550767..550967 (-) | 201 | WP_277697452.1 | helix-turn-helix domain-containing protein | - |
| PFZ59_RS02910 (PFZ59_02910) | - | 551173..551679 (+) | 507 | WP_277697765.1 | helix-turn-helix domain-containing protein | - |
| PFZ59_RS02915 (PFZ59_02915) | - | 551905..552009 (-) | 105 | WP_347176376.1 | type I toxin-antitoxin system Fst family toxin | - |
| PFZ59_RS02920 (PFZ59_02920) | - | 552344..553510 (+) | 1167 | WP_277697453.1 | site-specific integrase | - |
| PFZ59_RS02925 (PFZ59_02925) | yaaA | 553648..554031 (+) | 384 | WP_063077020.1 | S4 domain-containing protein YaaA | - |
| PFZ59_RS02930 (PFZ59_02930) | recF | 554034..555128 (+) | 1095 | WP_044683087.1 | DNA replication/repair protein RecF | - |
| PFZ59_RS02935 (PFZ59_02935) | guaB | 555199..556680 (-) | 1482 | WP_208581762.1 | IMP dehydrogenase | - |
| PFZ59_RS02940 (PFZ59_02940) | trpS | 556912..557937 (-) | 1026 | WP_014736602.1 | tryptophan--tRNA ligase | - |
| PFZ59_RS02945 (PFZ59_02945) | - | 558292..559164 (+) | 873 | WP_277697454.1 | YitT family protein | - |
| PFZ59_RS02950 (PFZ59_02950) | - | 559229..560851 (+) | 1623 | WP_012775415.1 | ATP-binding cassette domain-containing protein | - |
| PFZ59_RS02955 (PFZ59_02955) | - | 560888..563470 (+) | 2583 | WP_277697455.1 | YfhO family protein | - |
| PFZ59_RS02960 (PFZ59_02960) | - | 563536..564792 (+) | 1257 | WP_277697767.1 | ISL3 family transposase | - |
| PFZ59_RS02980 (PFZ59_02980) | - | 565289..565972 (-) | 684 | WP_208581756.1 | YoaK family protein | - |
| PFZ59_RS02985 (PFZ59_02985) | rlmH | 565997..566476 (-) | 480 | WP_004194528.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| PFZ59_RS02990 (PFZ59_02990) | htrA | 566650..567846 (+) | 1197 | WP_024384306.1 | trypsin-like peptidase domain-containing protein | Regulator |
| PFZ59_RS02995 (PFZ59_02995) | spo0J | 567907..568671 (+) | 765 | WP_012775418.1 | ParB/RepB/Spo0J family partition protein | Regulator |
| PFZ59_RS03000 (PFZ59_03000) | dnaA | 568874..570247 (+) | 1374 | WP_277697456.1 | chromosomal replication initiator protein DnaA | - |
| PFZ59_RS03005 (PFZ59_03005) | dnaN | 570401..571537 (+) | 1137 | WP_004194538.1 | DNA polymerase III subunit beta | - |
| PFZ59_RS03010 (PFZ59_03010) | - | 571629..572510 (+) | 882 | WP_208581750.1 | diacylglycerol kinase family protein | - |
| PFZ59_RS03015 (PFZ59_03015) | - | 572520..572723 (+) | 204 | WP_024394586.1 | DUF951 family protein | - |
| PFZ59_RS03020 (PFZ59_03020) | - | 572827..573186 (+) | 360 | WP_208581749.1 | helix-turn-helix transcriptional regulator | - |
Sequence
Protein
Download Length: 398 a.a. Molecular weight: 41866.89 Da Isoelectric Point: 4.4971
>NTDB_id=777085 PFZ59_RS02990 WP_024384306.1 566650..567846(+) (htrA) [Streptococcus suis strain SS/UPM/MY/F001]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTTVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKDGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTTVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKDGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE
Nucleotide
Download Length: 1197 bp
>NTDB_id=777085 PFZ59_RS02990 WP_024384306.1 566650..567846(+) (htrA) [Streptococcus suis strain SS/UPM/MY/F001]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTACTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGTGTCTACGCCAATACAGTTACTCAAGGTATTATTTCCAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGACAAACAATCTCAACCAATGCTATTCAAACCGATACAGCTATCAACCCAGGAAACTCTGGTGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCTGGTGTGGCTGTGGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAACTTGAAAAAGATGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
AATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTCTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTACTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGTGTCTACGCCAATACAGTTACTCAAGGTATTATTTCCAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ACGGACAAACAATCTCAACCAATGCTATTCAAACCGATACAGCTATCAACCCAGGAAACTCTGGTGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCTGGTGTGGCTGTGGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAACTTGAAAAAGATGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTAGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
AATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| htrA | Streptococcus mutans UA159 |
60.705 |
99.749 |
0.606 |
| htrA | Streptococcus gordonii str. Challis substr. CH1 |
60.506 |
99.246 |
0.6 |
| htrA | Streptococcus pneumoniae D39 |
57.761 |
98.744 |
0.57 |
| htrA | Streptococcus pneumoniae TIGR4 |
57.761 |
98.744 |
0.57 |
| htrA | Streptococcus mitis NCTC 12261 |
57.761 |
98.744 |
0.57 |
| htrA | Streptococcus pneumoniae R6 |
57.761 |
98.744 |
0.57 |
| htrA | Streptococcus pneumoniae Rx1 |
57.761 |
98.744 |
0.57 |