Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QVM92_RS09870 Genome accession   NZ_CP128963
Coordinates   2023819..2024475 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TUM1887     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2018819..2029475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QVM92_RS09840 (QVM92_09840) dcyD 2019699..2020685 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  QVM92_RS09845 (QVM92_09845) tcyL 2020700..2021368 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QVM92_RS09850 (QVM92_09850) tcyN 2021365..2022117 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QVM92_RS09855 (QVM92_09855) sdiA 2022347..2023069 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  QVM92_RS09860 (QVM92_09860) yecF 2023136..2023360 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QVM92_RS09865 (QVM92_09865) yecU 2023347..2023523 (-) 177 WP_000590347.1 protein YecU -
  QVM92_RS25695 - 2023606..2023677 (-) 72 Protein_1931 transcriptional regulator -
  QVM92_RS09870 (QVM92_09870) letA 2023819..2024475 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QVM92_RS09875 (QVM92_09875) uvrC 2024472..2026304 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QVM92_RS09880 (QVM92_09880) pgsA 2026361..2026909 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QVM92_RS09900 (QVM92_09900) yecA 2027559..2028224 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=776583 QVM92_RS09870 WP_000611335.1 2023819..2024475(+) (letA) [Escherichia coli strain TUM1887]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=776583 QVM92_RS09870 WP_000611335.1 2023819..2024475(+) (letA) [Escherichia coli strain TUM1887]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486