Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   PGS39_RS06640 Genome accession   NZ_CP116204
Coordinates   1286470..1288296 (+) Length   608 a.a.
NCBI ID   WP_000003390.1    Uniprot ID   A0A5M9H363
Organism   Bacillus paranthracis strain NVH_0075/95     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1281470..1293296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PGS39_RS06620 (PGS39_06620) - 1281780..1282454 (-) 675 WP_000362603.1 TerC family protein -
  PGS39_RS06625 (PGS39_06625) mecA 1282794..1283477 (+) 684 WP_000350710.1 adaptor protein MecA Regulator
  PGS39_RS06630 (PGS39_06630) - 1283550..1285094 (+) 1545 WP_000799204.1 cardiolipin synthase -
  PGS39_RS06635 (PGS39_06635) - 1285175..1286419 (+) 1245 WP_000612264.1 competence protein CoiA -
  PGS39_RS06640 (PGS39_06640) pepF 1286470..1288296 (+) 1827 WP_000003390.1 oligoendopeptidase F Regulator
  PGS39_RS06645 (PGS39_06645) - 1288414..1288587 (-) 174 WP_000754592.1 hypothetical protein -
  PGS39_RS06650 (PGS39_06650) - 1288817..1289710 (-) 894 WP_000360652.1 ClpXP adapter SpxH family protein -
  PGS39_RS06655 (PGS39_06655) - 1289710..1290108 (-) 399 WP_000043379.1 hypothetical protein -
  PGS39_RS06660 (PGS39_06660) - 1290289..1290867 (-) 579 WP_000191110.1 CYTH domain-containing protein -
  PGS39_RS06665 (PGS39_06665) - 1291014..1291385 (+) 372 WP_001180003.1 hypothetical protein -
  PGS39_RS06670 (PGS39_06670) - 1291416..1292054 (+) 639 WP_001081482.1 GTP pyrophosphokinase -
  PGS39_RS06675 (PGS39_06675) - 1292073..1292870 (+) 798 WP_000673184.1 NAD kinase -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 70289.54 Da        Isoelectric Point: 4.6399

>NTDB_id=776141 PGS39_RS06640 WP_000003390.1 1286470..1288296(+) (pepF) [Bacillus paranthracis strain NVH_0075/95]
MSEQNTAKTLPDRNEIEESSTWRLEDIFQTDAEWEQEFQAIKELLPKLTEFKGKLGDSANNLLEALQYEDEISMRLGKLY
TYAHMRYDQDTTNSVYQALNDRATNLYSQVSSSTAYIVPEILSISEDTLQTFLKENRDLSVYEHALEEITRQRPHVLSEA
EEALLAEASEVMSASSNTFGMLNNADLKFPSIKGEDGEEVEITHGRYIQFLESDDRRVREDAFKAVYETYGKYKNTFAST
LSGAVKRNNFNARVRKYDSARQAALSNNNIPEAVYDQLVQSVNDNLHLLHRYIDIRKRALGLDELHMYDLYTPLVPEVKM
NVKYEEAQDMLLKSLHVLGDEYVDILKEAYENRWVDVYENKGKRSGAYSSGAYGTNPYILMNWHDNVNNLFTLAHEFGHS
VHSYYTRKTQPHVYGDYSIFVAEVASTCNEALLNDYLLKTTEDKKERLYLLNHYLEGFRGTVFRQTMFAEFEHIIHKKVQ
EGHAVTPDMLTEIYYDLNKKYFGDALVIDEEIGLEWSRIPHFYYNYYVYQYATGFSAATALSKQILEEGQPAVERYINEF
LKAGSSDYPIEVLKKAGVDMASPEPVKEALQVFEEKLNELEALLFEEK

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=776141 PGS39_RS06640 WP_000003390.1 1286470..1288296(+) (pepF) [Bacillus paranthracis strain NVH_0075/95]
ATGTCTGAACAAAACACAGCAAAAACATTACCGGATCGTAACGAAATTGAAGAATCAAGTACGTGGCGATTAGAAGATAT
TTTCCAAACAGATGCAGAATGGGAACAAGAATTCCAAGCTATTAAAGAGCTATTACCGAAGTTAACTGAATTTAAAGGGA
AACTTGGTGACTCTGCGAACAATTTACTTGAAGCATTGCAATATGAAGATGAAATTTCAATGCGATTAGGTAAGCTATAT
ACATATGCACATATGCGTTACGATCAAGATACAACAAACTCTGTGTATCAAGCGTTAAATGACCGTGCAACAAATTTATA
TTCACAAGTATCTAGTAGCACAGCATATATTGTGCCTGAAATTTTATCGATTTCAGAAGATACATTGCAAACATTCTTGA
AAGAAAATAGAGACTTAAGTGTATATGAACATGCGTTAGAAGAAATTACGCGTCAACGCCCTCACGTATTATCTGAAGCG
GAAGAGGCTTTATTAGCAGAAGCATCTGAAGTAATGAGTGCGTCAAGTAATACATTTGGTATGTTGAATAATGCGGATTT
GAAATTCCCATCTATTAAAGGTGAGGATGGAGAAGAAGTAGAAATTACACATGGCCGTTACATTCAGTTTTTAGAAAGTG
ATGATCGTCGTGTGCGTGAAGATGCATTCAAAGCTGTATATGAAACGTACGGGAAATATAAGAACACATTTGCAAGTACG
TTAAGCGGAGCTGTAAAGCGTAATAACTTTAATGCACGCGTTCGTAAATATGACTCTGCACGTCAAGCAGCATTAAGTAA
TAATAATATTCCTGAAGCGGTGTATGATCAACTTGTTCAATCTGTAAATGACAATTTACACTTGCTACATCGTTACATTG
ATATTCGTAAGCGTGCACTAGGGCTTGATGAGCTTCATATGTATGATTTATATACACCACTTGTACCAGAAGTGAAAATG
AATGTGAAGTATGAAGAAGCGCAAGACATGTTATTAAAGTCTTTACATGTACTTGGTGATGAGTATGTTGATATTTTGAA
AGAAGCATATGAAAATCGCTGGGTAGATGTGTATGAGAATAAAGGAAAACGAAGCGGAGCATATTCATCTGGTGCCTATG
GAACAAATCCTTATATTTTAATGAACTGGCATGATAATGTAAATAATTTATTTACACTTGCTCATGAATTTGGTCATTCT
GTCCATAGTTACTACACAAGAAAAACGCAGCCGCACGTATACGGGGATTATTCAATCTTTGTTGCGGAAGTAGCATCAAC
TTGTAATGAAGCGCTTCTAAACGATTATTTATTAAAAACGACAGAAGATAAGAAAGAGCGTCTATACTTATTAAATCATT
ATTTAGAAGGATTCCGTGGTACTGTATTCCGTCAAACGATGTTCGCAGAGTTTGAGCATATTATTCATAAGAAAGTACAA
GAGGGACATGCGGTAACACCAGACATGCTAACGGAGATCTACTATGATTTAAATAAGAAATATTTCGGTGATGCTTTAGT
AATTGATGAAGAAATTGGTTTAGAGTGGTCTCGTATTCCGCACTTCTACTACAACTATTACGTATACCAATACGCAACAG
GATTTAGTGCAGCAACGGCTCTATCTAAACAAATTTTAGAAGAAGGGCAACCAGCAGTAGAACGTTACATTAATGAGTTC
TTAAAAGCAGGAAGCTCAGATTACCCAATTGAAGTGCTGAAAAAAGCTGGAGTAGATATGGCATCTCCAGAACCGGTAAA
AGAAGCATTGCAAGTATTTGAAGAGAAATTAAATGAATTAGAAGCATTATTATTTGAAGAGAAGTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(211-591)

Oligopeptidase F (Peptidase_M3_N)

(120-189)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5M9H363

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50.084

97.533

0.488