Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   QVN05_RS22795 Genome accession   NZ_CP128912
Coordinates   4691295..4694117 (+) Length   940 a.a.
NCBI ID   WP_000357763.1    Uniprot ID   A0A0H2Z4Q6
Organism   Escherichia coli strain TUM13773     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4686295..4699117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QVN05_RS22770 (QVN05_22770) soxR 4687233..4687697 (-) 465 WP_289415187.1 redox-sensitive transcriptional activator SoxR -
  QVN05_RS22775 (QVN05_22775) soxS 4687783..4688106 (+) 324 WP_000019358.1 superoxide response transcriptional regulator SoxS -
  QVN05_RS22780 (QVN05_22780) pdeC 4688142..4689695 (-) 1554 WP_289942588.1 c-di-GMP phosphodiesterase PdeC -
  QVN05_RS22785 (QVN05_22785) yjcB 4690124..4690405 (+) 282 WP_001296643.1 YjcB family protein -
  QVN05_RS22790 (QVN05_22790) ssb 4690504..4691040 (-) 537 WP_000168305.1 single-stranded DNA-binding protein SSB1 Machinery gene
  QVN05_RS22795 (QVN05_22795) uvrA 4691295..4694117 (+) 2823 WP_000357763.1 excinuclease ABC subunit UvrA Machinery gene
  QVN05_RS22800 (QVN05_22800) yjbR 4694152..4694508 (-) 357 WP_000155657.1 MmcQ/YjbR family DNA-binding protein -
  QVN05_RS22805 (QVN05_22805) yjbQ 4694512..4694928 (-) 417 WP_000270369.1 secondary thiamine-phosphate synthase enzyme YjbQ -
  QVN05_RS22810 (QVN05_22810) aphA 4695039..4695752 (-) 714 WP_001226933.1 acid phosphatase AphA -
  QVN05_RS22815 (QVN05_22815) - 4696029..4697849 (+) 1821 WP_000704410.1 ATP-binding protein -

Sequence

Protein


Download         Length: 940 a.a.        Molecular weight: 103883.54 Da        Isoelectric Point: 6.6065

>NTDB_id=775795 QVN05_RS22795 WP_000357763.1 4691295..4694117(+) (uvrA) [Escherichia coli strain TUM13773]
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML

Nucleotide


Download         Length: 2823 bp        

>NTDB_id=775795 QVN05_RS22795 WP_000357763.1 4691295..4694117(+) (uvrA) [Escherichia coli strain TUM13773]
ATGGATAAGATCGAAGTTCGGGGCGCCCGCACCCATAATCTCAAAAACATCAACCTCGTTATCCCCCGCGACAAGCTTAT
TGTCGTGACCGGGCTTTCGGGTTCTGGCAAATCCTCGCTCGCTTTCGACACCTTATATGCCGAAGGGCAGCGCCGTTACG
TTGAATCCCTTTCCGCCTACGCGCGGCAGTTTCTGTCACTGATGGAGAAGCCGGACGTCGACCATATTGAAGGGCTTTCT
CCTGCCATCTCAATTGAGCAGAAATCGACGTCTCATAACCCGCGCTCTACGGTGGGGACAATCACCGAAATCCACGACTA
TTTGCGTCTGCTGTACGCTCGCGTTGGTGAGCCACGCTGCCCGGACCACGATGTACCGCTGGCGGCGCAAACCGTCAGTC
AGATGGTGGATAACGTGTTGTCCCAGCCGGAAGGCAAGCGTCTGATGCTGCTCGCGCCAATCATTAAAGAGCGCAAAGGC
GAACACACCAAAACGCTGGAGAACCTGGCAAGCCAGGGTTACATCCGTGCTCGTATTGATGGCGAAGTCTGCGATCTTTC
CGATCCGCCGAAACTGGAATTGCAAAAGAAACATACCATTGAAGTGGTGGTTGATCGCTTCAAAGTGCGTGACGATCTTA
CCCAACGTCTTGCCGAGTCGTTTGAAACCGCGCTGGAGCTTTCCGGTGGTACCGCGGTAGTGGCGGATATGGACGACCCG
AAAGCGGAAGAGCTGCTGTTCTCCGCCAACTTTGCCTGCCCGATTTGCGGTTACAGTATGCGCGAGCTGGAACCTCGCCT
GTTTTCATTTAACAACCCGGCGGGAGCCTGCCCGACCTGTGACGGTCTTGGCGTACAGCAATATTTCGATCCTGACCGCG
TGATCCAGAATCCGGAATTGTCGCTGGCTGGCGGTGCGATCCGTGGCTGGGATCGCCGCAACTTCTATTATTTCCAGATG
CTGAAATCGCTGGCAGATCACTATAAGTTCGACGTCGAAGCGCCGTGGGGCAGCCTGAGCGCGAACGTGCATAAAGTGGT
GTTGTACGGTTCTGGCAAAGAAAATATTGAATTCAAATACATGAACGATCGTGGCGATACCTCCATTCGTCGTCATCCGT
TCGAAGGCGTGCTGCACAATATGGAGCGCCGTTATAAAGAGACGGAATCCAGTGCGGTACGTGAAGAATTAGCCAAGTTT
ATCAGCAATCGTCCGTGCGCCAGCTGCGAAGGAACCCGTCTGCGTCGGGAAGCACGCCACGTGTATGTCGAGAATACGCC
GCTGCCCGCCATCTCCGACATGAGCATCGGTCATGCGATGGAATTCTTCAACAATCTCAAACTCGCAGGTCAGCGGGCGA
AGATTGCAGAAAAAATCCTTAAAGAGATCGGCGATCGTCTGAAATTCCTCGTTAACGTCGGCCTGAATTACCTGACACTT
TCCCGCTCGGCAGAGACACTTTCCGGCGGTGAAGCCCAGCGTATTCGTCTGGCAAGCCAGATTGGTGCAGGCCTGGTTGG
CGTGATGTACGTGCTGGATGAGCCGTCTATCGGCCTGCACCAGCGCGATAACGAGCGCCTGCTGGGTACGCTTATCCATC
TGCGCGATCTCGGTAATACCGTGATTGTGGTGGAGCACGACGAAGACGCGATTCGCGCCGCTGATCATGTGATCGATATC
GGTCCGGGTGCGGGTGTTCACGGCGGTGAAGTGGTCGCGGAAGGTCCACTGGAAGCGATTATGGCGGTGCCTGAGTCGTT
GACCGGGCAGTACATGAGCGGTAAACGCAAGATTGAGGTGCCGAAGAAGCGCGTTCCGGCAAATCCGGAAAAAGTGCTGA
AGCTGACAGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGTCTGTTTACTTGCATCACAGGG
GTTTCAGGTTCCGGTAAATCGACGCTGATTAACGACACACTGTTCCCGATTGCCCAACGCCAGTTGAATGGTGCGACCAT
CGCCGAACCGGCACCGTATCGCGATATTCAGGGACTGGAGCATTTCGATAAAGTGATCGATATCGACCAAAGCCCAATTG
GTCGTACTCCGCGTTCTAACCCGGCGACCTATACCGGCGTGTTTACACCTGTGCGCGAACTGTTTGCGGGCGTACCGGAA
TCCCGTGCGCGCGGCTATACGCCAGGACGTTTCAGCTTTAACGTCCGTGGCGGACGCTGCGAGGCCTGTCAGGGCGACGG
CGTGATCAAAGTGGAGATGCACTTCCTGCCGGACATTTACGTACCGTGCGACCAGTGCAAAGGCAAACGCTATAACCGTG
AAACGCTGGAGATTAAGTACAAAGGCAAAACCATCCACGAAGTGCTGGATATGACCATCGAAGAGGCGCGTGAGTTCTTT
GATGCGGTGCCAGCTCTGGCGCGTAAGCTGCAAACGCTGATGGATGTTGGCCTGACGTACATTCGCCTCGGGCAGTCCGC
AACCACACTTTCTGGTGGTGAAGCCCAGCGCGTGAAGCTGGCGCGTGAGCTGTCAAAACGCGGCACCGGGCAGACGCTGT
ATATTCTCGACGAGCCGACCACCGGTCTGCACTTCGCCGATATTCAGCAACTGCTCGACGTACTGCATAAACTGCGCGAT
CAGGGCAATACCATTGTGGTAATTGAGCACAATCTCGACGTGATCAAAACCGCTGACTGGATTGTCGACCTGGGACCGGA
AGGCGGCAGTGGGGGCGGCGAAATCCTCGTCTCCGGTACGCCAGAAACCGTCGCAGAGTGCGAAGCTTCGCATACGGCGC
GCTTCCTCAAGCCGATGCTGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(290-399)

ABC transporter (ABC_tran)

(806-860)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4Q6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

57.476

100

0.577
  uvrA Streptococcus pneumoniae TIGR4

57.476

100

0.577
  uvrA Streptococcus pneumoniae D39

57.476

100

0.577