Detailed information NTG0775101

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: PF977_RS08325
• Genome accession: NZ_CP116012
• Coordinates: 1600434..1602764 (+)
• Length: 776 a.a.
• NCBI ID: WP_074794436.1
• Uniprot ID: A0A8E0SBN0
• Organism: Bacillus subtilis strain SRCM124333
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1595434..1607764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PF977_RS08285 (PF977_08285)	yhbY	1595678..1595968 (+)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-
PF977_RS08290 (PF977_08290)	nadD	1595980..1596549 (+)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
PF977_RS08295 (PF977_08295)	yqeK	1596539..1597099 (+)	561	WP_004399059.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
PF977_RS08300 (PF977_08300)	rsfS	1597117..1597473 (+)	357	WP_014480315.1	ribosome silencing factor	-
PF977_RS08305 (PF977_08305)	yqeM	1597470..1598213 (+)	744	WP_015714290.1	class I SAM-dependent DNA methyltransferase	-
PF977_RS08310 (PF977_08310)	comER	1598279..1599100 (-)	822	WP_015714289.1	late competence protein ComER	-
PF977_RS08315 (PF977_08315)	comEA	1599184..1599801 (+)	618	WP_004398514.1	competence protein ComEA	Machinery gene
PF977_RS08320 (PF977_08320)	comEB	1599868..1600437 (+)	570	WP_015714288.1	ComE operon protein 2	-
PF977_RS08325 (PF977_08325)	comEC	1600434..1602764 (+)	2331	WP_074794436.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
PF977_RS08330 (PF977_08330)	yqzM	1602804..1602938 (-)	135	WP_003229983.1	YqzM family protein	-
PF977_RS08335 (PF977_08335)	-	1602979..1603128 (+)	150	WP_003229985.1	hypothetical protein	-
PF977_RS08340 (PF977_08340)	holA	1603168..1604211 (+)	1044	WP_015714286.1	DNA polymerase III subunit delta	-
PF977_RS08345 (PF977_08345)	rpsT	1604226..1604492 (-)	267	WP_003229989.1	30S ribosomal protein S20	-
PF977_RS08350 (PF977_08350)	gpr	1604696..1605802 (+)	1107	WP_015714285.1	GPR endopeptidase	-
PF977_RS08355 (PF977_08355)	spoIIP	1605865..1607070 (+)	1206	WP_014477383.1	spore autolysin SpoIIP	-
PF977_RS08360 (PF977_08360)	yqxA	1607087..1607425 (+)	339	WP_014477382.1	YqxA family protein	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86642.27 Da
• Isoelectric Point: 7.2477

>NTDB_id=775101 PF977_RS08325 WP_074794436.1 1600434..1602764(+) (comEC) [Bacillus subtilis strain SRCM124333]
MMNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMVVKTPDKEKWAAAYRILSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHTISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFQQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSASFGRLFFSWFDLLISWTNRLITNIADVDVFTIMIAHPAPVLLFLFTVAIILLLMAIEKRSLSQLMITGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPE
TPDPASKNNSSLVLWMETGVLSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQKVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=775101 PF977_RS08325 WP_074794436.1 1600434..1602764(+) (comEC) [Bacillus subtilis strain SRCM124333]
GTGATGAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGGTGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCTGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGAGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATACCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGACGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTTTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGCCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCAGCA
GGTTAAAACCTCCTTGGGACAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTTCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGCTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGATGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTTGCGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGATAACCGGCGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGTCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGAA
ACACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGTTCTGAGCTGGATTTTGACGGG
TGATCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAAAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Competence protein (Competence) (208-469)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	97.809	100	0.978