Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QUS00_RS10855 Genome accession   NZ_CP128581
Coordinates   1960447..1961103 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain VG888-46E9     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955447..1966103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUS00_RS10825 (QUS00_10825) dcyD 1956327..1957313 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QUS00_RS10830 (QUS00_10830) tcyL 1957328..1957996 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QUS00_RS10835 (QUS00_10835) tcyN 1957993..1958745 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QUS00_RS10840 (QUS00_10840) sdiA 1958975..1959697 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  QUS00_RS10845 (QUS00_10845) yecF 1959764..1959988 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QUS00_RS10850 (QUS00_10850) yecU 1959975..1960151 (-) 177 WP_001307856.1 protein YecU -
  QUS00_RS25060 - 1960234..1960305 (-) 72 Protein_1904 transcriptional regulator -
  QUS00_RS10855 (QUS00_10855) letA 1960447..1961103 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QUS00_RS10860 (QUS00_10860) uvrC 1961100..1962932 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QUS00_RS10865 (QUS00_10865) pgsA 1962989..1963537 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QUS00_RS10885 (QUS00_10885) - 1964233..1964973 (-) 741 WP_096260496.1 hypothetical protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=774539 QUS00_RS10855 WP_000611335.1 1960447..1961103(+) (letA) [Escherichia coli strain VG888-46E9]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=774539 QUS00_RS10855 WP_000611335.1 1960447..1961103(+) (letA) [Escherichia coli strain VG888-46E9]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486