Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QUC24_RS12575 Genome accession   NZ_CP128506
Coordinates   2646785..2647429 (+) Length   214 a.a.
NCBI ID   WP_003090351.1    Uniprot ID   A0A0H2ZC55
Organism   Pseudomonas aeruginosa strain Fe11-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2641785..2652429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QUC24_RS12560 (QUC24_12560) - 2642419..2643633 (+) 1215 WP_023088273.1 MFS transporter -
  QUC24_RS12565 (QUC24_12565) - 2643649..2644677 (-) 1029 WP_003097554.1 AraC family transcriptional regulator -
  QUC24_RS12570 (QUC24_12570) pqsH 2645295..2646443 (+) 1149 WP_017149103.1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase -
  QUC24_RS12575 (QUC24_12575) letA 2646785..2647429 (+) 645 WP_003090351.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QUC24_RS12580 (QUC24_12580) uvrC 2647430..2649256 (+) 1827 WP_003097551.1 excinuclease ABC subunit UvrC -
  QUC24_RS12585 (QUC24_12585) pgsA 2649290..2649850 (+) 561 WP_003090349.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QUC24_RS12595 (QUC24_12595) - 2650251..2650504 (-) 254 Protein_2486 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23608.53 Da        Isoelectric Point: 6.1073

>NTDB_id=774251 QUC24_RS12575 WP_003090351.1 2646785..2647429(+) (letA) [Pseudomonas aeruginosa strain Fe11-1]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=774251 QUC24_RS12575 WP_003090351.1 2646785..2647429(+) (letA) [Pseudomonas aeruginosa strain Fe11-1]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAACTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCCTGGAGGCAACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGATCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTATATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAGCTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

54.502

98.598

0.537
  letA Legionella pneumophila strain ERS1305867

54.502

98.598

0.537