Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QRS93_RS05745 Genome accession   NZ_CP127842
Coordinates   1145694..1147478 (-) Length   594 a.a.
NCBI ID   WP_015017082.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1140694..1152478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRS93_RS05730 (QRS93_05730) pepV 1141481..1142890 (-) 1410 WP_015017081.1 dipeptidase PepV -
  QRS93_RS05735 (QRS93_05735) - 1143068..1143670 (-) 603 WP_003054310.1 nitroreductase family protein -
  QRS93_RS05740 (QRS93_05740) - 1143983..1145641 (+) 1659 Protein_1089 thiamine pyrophosphate-dependent enzyme -
  QRS93_RS05745 (QRS93_05745) uvrC 1145694..1147478 (-) 1785 WP_015017082.1 excinuclease ABC subunit UvrC Machinery gene
  QRS93_RS05750 (QRS93_05750) - 1147608..1147757 (-) 150 WP_042357931.1 HAD hydrolase family protein -
  QRS93_RS05755 (QRS93_05755) - 1147813..1149189 (-) 1377 WP_042357932.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  QRS93_RS05760 (QRS93_05760) - 1149267..1149974 (-) 708 WP_015017084.1 YjjG family noncanonical pyrimidine nucleotidase -
  QRS93_RS05765 (QRS93_05765) - 1150022..1150693 (-) 672 WP_015017085.1 DUF1524 domain-containing protein -
  QRS93_RS05770 (QRS93_05770) - 1150911..1151477 (-) 567 WP_003058443.1 sugar O-acetyltransferase -
  QRS93_RS05775 (QRS93_05775) - 1151493..1152167 (-) 675 WP_015017086.1 HAD family phosphatase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 67994.69 Da        Isoelectric Point: 9.4030

>NTDB_id=772936 QRS93_RS05745 WP_015017082.1 1145694..1147478(-) (uvrC) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVNKVCF
YYHLGQCCAHTICHTGKAYWDGLVEDVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIAIMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNEAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPQRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGYLLGIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVIFRRYSRVKHEGLVAPDLIIIDGGLGQVNAAREVIEDRLGLTIPIAGLQ
KNDKHQTHELLFGKPLEVVPLPRNSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQILLKHFKTM
TAIAAASPDEIHSLGIPRAVASAVHQHLTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=772936 QRS93_RS05745 WP_015017082.1 1145694..1147478(-) (uvrC) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-F37]
ATGAATGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGTCCTGGTTGCTACTTGCATAAGGACAAAGAGGGAAC
CATTATCTATGTAGGTAAAGCTAAGAATTTGAAGAACCGAGTGCGATCTTATTTTCGTGGTAGCCATGATACTAAGACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTGACCGAATCAAATACTGAGGCTCTCTTGCTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAGTATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GACCTTTCCTCGCTTGCTTATTACGAGACAGATTAAGAAAAATGACGGTCTATATTTCGGGCCCTATCCAGATTCGTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGCATTTTTCCCTTTAAGAAATGTAAAAACCCTGTCAATAAGGTCTGTTTT
TATTACCATTTAGGACAGTGTTGTGCTCATACTATCTGCCATACAGGTAAGGCTTATTGGGATGGTCTGGTAGAGGATGT
CAAACACTTTTTGAATGGTAAGGATGACAAGATTATTGATGGGCTGCGGGCAAAAATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCATCATGCGCACCAAGCAGCGGGTGATGAGTAAG
GACTTGCAAGACAGAGATATTTTTGGCTACTTTGTTGACAAGGGCTGGATGTGCGTACAGGTTTTCTTTGTCCGTCAAGG
GAAATTAATTCAGCGGGATGTTAACCTTTTTCCTTACTATAACGAGGCAGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTATCAAGATAAACAGCATTTTATCCCCAAAGAAGTCTTTATTCCAGAAGCTATTGACGAAGAACTAGTAGCGGCCATT
GTGCCAACTAAAATCATCAAGCCTCAACGGGGTGAGAAAAAACAATTGGTGGCTTTGGCGACCAAGAATGCACGTGTTAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCCATTGACAATCTAGGCTACTTGTTAG
GAATTGACAAGCCAGTCCGGATTGAGGCTTTTGATAATTCCAATATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGCCCAGATGATTATGCCAG
CATGAGGGAAGTGATTTTTCGAAGGTATAGCCGCGTTAAACATGAAGGACTGGTAGCTCCTGATTTAATCATCATTGATG
GTGGGCTAGGGCAGGTCAATGCGGCCAGAGAAGTGATTGAAGACCGACTAGGTTTAACGATTCCTATTGCGGGTTTGCAA
AAAAATGATAAGCACCAGACCCATGAATTGCTCTTTGGAAAGCCACTCGAGGTAGTCCCCTTACCCCGTAATTCAGAAGA
ATTTTTCCTCTTGCATCGCATCCAAGATGAGGTGCACCGCTTTGCGATTACTTTCCACCGACAGGTTCGCAGTAAAAATT
CATTCTCTTCGAAATTGGATAAGATTCCAGGACTAGGTCCGAAGCGCAAGCAGATACTGCTTAAACATTTTAAAACCATG
ACAGCCATTGCAGCAGCTAGTCCAGATGAGATTCATTCGTTAGGGATTCCTAGGGCGGTGGCATCAGCTGTCCATCAGCA
TCTGACAGACAGTCAGCAAAGTTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

UvrB/uvrC motif (UVR)

(196-227)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.722

99.158

0.751
  uvrC Streptococcus pneumoniae R6

75.382

99.158

0.747
  uvrC Streptococcus pneumoniae D39

75.382

99.158

0.747