Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQ475_RS14850 Genome accession   NZ_CP127493
Coordinates   3037182..3037838 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain PS00260.4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3032182..3042838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQ475_RS14820 (QQ475_14790) yecA 3033433..3034098 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  QQ475_RS14840 (QQ475_14810) pgsA 3034748..3035296 (-) 549 WP_331327315.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQ475_RS14845 (QQ475_14815) uvrC 3035353..3037185 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQ475_RS14850 (QQ475_14820) letA 3037182..3037838 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQ475_RS14855 - 3037980..3038051 (+) 72 Protein_2909 transcriptional regulator -
  QQ475_RS14860 (QQ475_14825) yecU 3038134..3038310 (+) 177 WP_000590347.1 protein YecU -
  QQ475_RS14865 (QQ475_14830) yecF 3038297..3038521 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQ475_RS14870 (QQ475_14835) sdiA 3038589..3039311 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  QQ475_RS14875 (QQ475_14840) tcyN 3039541..3040293 (-) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQ475_RS14880 (QQ475_14845) tcyL 3040290..3040958 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QQ475_RS14885 (QQ475_14850) dcyD 3040973..3041959 (-) 987 WP_001128218.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=772793 QQ475_RS14850 WP_000611335.1 3037182..3037838(-) (letA) [Escherichia coli strain PS00260.4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=772793 QQ475_RS14850 WP_000611335.1 3037182..3037838(-) (letA) [Escherichia coli strain PS00260.4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486