Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QRX37_RS07225 Genome accession   NZ_CP127324
Coordinates   1445125..1445781 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 980-2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1440125..1450781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRX37_RS07195 (QRX37_07170) dcyD 1441005..1441991 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  QRX37_RS07200 (QRX37_07175) tcyL 1442006..1442674 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QRX37_RS07205 (QRX37_07180) tcyN 1442671..1443423 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QRX37_RS07210 (QRX37_07185) sdiA 1443653..1444375 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  QRX37_RS07215 (QRX37_07190) yecF 1444442..1444666 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QRX37_RS07220 (QRX37_07195) yecU 1444653..1444829 (-) 177 WP_032160694.1 protein YecU -
  QRX37_RS07225 (QRX37_07200) letA 1445125..1445781 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QRX37_RS07230 (QRX37_07205) uvrC 1445778..1447610 (+) 1833 WP_075862275.1 excinuclease ABC subunit UvrC Machinery gene
  QRX37_RS07235 (QRX37_07210) pgsA 1447667..1448215 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QRX37_RS07255 (QRX37_07230) yecA 1448864..1449529 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=772294 QRX37_RS07225 WP_000611328.1 1445125..1445781(+) (letA) [Escherichia coli strain 980-2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=772294 QRX37_RS07225 WP_000611328.1 1445125..1445781(+) (letA) [Escherichia coli strain 980-2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482