Detailed information NTG0772243

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: PDI54_RS13595
• Genome accession: NZ_CP115472
• Coordinates: 2731086..2731973 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AF4001
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2726086..2736973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI54_RS13565 (PDI54_13565)	-	2726105..2726197 (+)	93	WP_010956583.1	hypothetical protein	-
PDI54_RS13570 (PDI54_13570)	-	2726305..2726802 (-)	498	WP_001065268.1	glutathione peroxidase	-
PDI54_RS13575 (PDI54_13575)	-	2726812..2727072 (-)	261	WP_001791974.1	hypothetical protein	-
PDI54_RS13580 (PDI54_13580)	-	2727454..2727567 (-)	114	Protein_2640	hypothetical protein	-
PDI54_RS13585 (PDI54_13585)	-	2728226..2730226 (-)	2001	WP_000776750.1	ABC transporter permease	-
PDI54_RS13590 (PDI54_13590)	-	2730223..2730978 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
PDI54_RS13595 (PDI54_13595)	braS	2731086..2731973 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
PDI54_RS13600 (PDI54_13600)	braR	2731984..2732649 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
PDI54_RS13605 (PDI54_13605)	-	2732675..2732875 (-)	201	WP_000604730.1	hypothetical protein	-
PDI54_RS13610 (PDI54_13610)	-	2733073..2734497 (+)	1425	WP_000953755.1	alkaline phosphatase	-
PDI54_RS14080	-	2734557..2734658 (-)	102	WP_000731976.1	SE2200 family small protein	-
PDI54_RS13620 (PDI54_13620)	-	2734780..2735235 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
PDI54_RS13625 (PDI54_13625)	-	2735480..2736241 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=772243 PDI54_RS13595 WP_000143425.1 2731086..2731973(-) (braS) [Staphylococcus aureus strain AF4001]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=772243 PDI54_RS13595 WP_000143425.1 2731086..2731973(-) (braS) [Staphylococcus aureus strain AF4001]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1