Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QRM71_RS06450 Genome accession   NZ_CP127316
Coordinates   1257991..1258647 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Ch1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1252991..1263647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRM71_RS06420 (QRM71_06420) yecA 1254242..1254907 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  QRM71_RS06440 (QRM71_06440) pgsA 1255557..1256105 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QRM71_RS06445 (QRM71_06445) uvrC 1256162..1257994 (-) 1833 WP_046425971.1 excinuclease ABC subunit UvrC Machinery gene
  QRM71_RS06450 (QRM71_06450) letA 1257991..1258647 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QRM71_RS27985 - 1258789..1258860 (+) 72 Protein_1274 transcriptional regulator -
  QRM71_RS06455 (QRM71_06455) yecU 1258943..1259119 (+) 177 WP_000590347.1 protein YecU -
  QRM71_RS06460 (QRM71_06460) yecF 1259106..1259330 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QRM71_RS06465 (QRM71_06465) sdiA 1259397..1260119 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  QRM71_RS06470 (QRM71_06470) tcyN 1260349..1261101 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QRM71_RS06475 (QRM71_06475) tcyL 1261098..1261766 (-) 669 WP_032162420.1 cystine ABC transporter permease -
  QRM71_RS06480 (QRM71_06480) dcyD 1261781..1262767 (-) 987 WP_001128238.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=772202 QRM71_RS06450 WP_000611335.1 1257991..1258647(-) (letA) [Escherichia coli strain Ch1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=772202 QRM71_RS06450 WP_000611335.1 1257991..1258647(-) (letA) [Escherichia coli strain Ch1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAACGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486