Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QRM68_RS17950 Genome accession   NZ_CP127303
Coordinates   3335570..3336226 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain APEC37     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3330570..3341226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRM68_RS17920 (QRM68_17920) dcyD 3331449..3332435 (+) 987 WP_001724631.1 D-cysteine desulfhydrase -
  QRM68_RS17925 (QRM68_17925) tcyL 3332450..3333118 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QRM68_RS17930 (QRM68_17930) tcyN 3333115..3333867 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QRM68_RS17935 (QRM68_17935) sdiA 3334097..3334819 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QRM68_RS17940 (QRM68_17940) yecF 3334887..3335111 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QRM68_RS17945 (QRM68_17945) yecU 3335098..3335274 (-) 177 WP_000590344.1 protein YecU -
  QRM68_RS26130 - 3335312..3335428 (-) 117 WP_001302039.1 hypothetical protein -
  QRM68_RS17950 (QRM68_17950) letA 3335570..3336226 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QRM68_RS17955 (QRM68_17955) uvrC 3336223..3338055 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  QRM68_RS17960 (QRM68_17960) pgsA 3338112..3338660 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QRM68_RS17980 (QRM68_17980) yecA 3339310..3339975 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=772004 QRM68_RS17950 WP_000611328.1 3335570..3336226(+) (letA) [Escherichia coli strain APEC37]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=772004 QRM68_RS17950 WP_000611328.1 3335570..3336226(+) (letA) [Escherichia coli strain APEC37]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482