Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QRM67_RS11725 Genome accession   NZ_CP127297
Coordinates   2395580..2396236 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain APEC20/16     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2390580..2401236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QRM67_RS11695 (QRM67_11695) dcyD 2391460..2392446 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QRM67_RS11700 (QRM67_11700) tcyL 2392461..2393129 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QRM67_RS11705 (QRM67_11705) tcyN 2393126..2393878 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QRM67_RS11710 (QRM67_11710) sdiA 2394108..2394830 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  QRM67_RS11715 (QRM67_11715) yecF 2394897..2395121 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QRM67_RS11720 (QRM67_11720) yecU 2395108..2395284 (-) 177 WP_000590347.1 protein YecU -
  QRM67_RS26255 - 2395367..2395438 (-) 72 Protein_2273 transcriptional regulator -
  QRM67_RS11725 (QRM67_11725) letA 2395580..2396236 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QRM67_RS11730 (QRM67_11730) uvrC 2396233..2398065 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QRM67_RS11735 (QRM67_11735) pgsA 2398122..2398670 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QRM67_RS11755 (QRM67_11755) yecA 2399320..2399985 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=771916 QRM67_RS11725 WP_000611335.1 2395580..2396236(+) (letA) [Escherichia coli strain APEC20/16]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=771916 QRM67_RS11725 WP_000611335.1 2395580..2396236(+) (letA) [Escherichia coli strain APEC20/16]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486