Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMY53_RS20690 Genome accession   NZ_CP127265
Coordinates   4171700..4172356 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli TW14425     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4166700..4177356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY53_RS20655 (QMY53_04067) dcyD 4167579..4168565 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  QMY53_RS20660 (QMY53_04068) tcyL 4168580..4169248 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QMY53_RS20665 (QMY53_04069) tcyN 4169245..4169997 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QMY53_RS20670 (QMY53_04070) sdiA 4170227..4170949 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QMY53_RS20675 (QMY53_04071) yecF 4171017..4171241 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QMY53_RS20680 yecU 4171228..4171404 (-) 177 WP_000590347.1 protein YecU -
  QMY53_RS20685 - 4171487..4171558 (-) 72 Protein_4022 transcriptional regulator -
  QMY53_RS20690 (QMY53_04072) letA 4171700..4172356 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QMY53_RS20695 (QMY53_04073) uvrC 4172353..4174185 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QMY53_RS20700 (QMY53_04074) pgsA 4174242..4174790 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QMY53_RS20720 (QMY53_04078) yecA 4175440..4176105 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=771857 QMY53_RS20690 WP_000611335.1 4171700..4172356(+) (letA) [Escherichia coli TW14425]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=771857 QMY53_RS20690 WP_000611335.1 4171700..4172356(+) (letA) [Escherichia coli TW14425]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486