Detailed information NTG0771602

Bioinformatically predicted

Overview

• Name: pilS
• Type: Regulator
• Locus tag: PCP76_RS01570
• Genome accession: NZ_CP115297
• Coordinates: 317804..319396 (-)
• Length: 530 a.a.
• NCBI ID: WP_039028118.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain 135
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	315312..337105	317804..319396	within	0

Gene organization within MGE regions

Location: 315312..337105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PCP76_RS01560 (PCP76_01560)	thiO	315312..316406 (+)	1095	WP_039028141.1	glycine oxidase ThiO	-
PCP76_RS01565 (PCP76_01565)	pilR	316452..317789 (-)	1338	WP_073649712.1	two-component system response regulator PilR	Regulator
PCP76_RS01570 (PCP76_01570)	pilS	317804..319396 (-)	1593	WP_039028118.1	two-component system sensor histidine kinase PilS	Regulator
PCP76_RS01575 (PCP76_01575)	-	319386..319631 (-)	246	WP_003102591.1	PP0621 family protein	-
PCP76_RS01580 (PCP76_01580)	-	319788..320813 (-)	1026	WP_033972916.1	outer membrane protein assembly factor BamD	-
PCP76_RS01585 (PCP76_01585)	rluD	320959..321921 (+)	963	WP_033972915.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PCP76_RS01590 (PCP76_01590)	pgeF	321918..322646 (+)	729	WP_058179501.1	peptidoglycan editing factor PgeF	-
PCP76_RS01595 (PCP76_01595)	clpB	322802..325366 (+)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	-
PCP76_RS01615 (PCP76_01615)	-	326036..326547 (-)	512	Protein_309	IS3 family transposase	-
PCP76_RS29775	-	327350..327592 (+)	243	Protein_310	hypothetical protein	-
PCP76_RS01625 (PCP76_01625)	-	327951..328163 (+)	213	WP_211904283.1	fimbrial protein	-
PCP76_RS01630	-	328802..328999 (+)	198	WP_071546846.1	hypothetical protein	-
PCP76_RS01635 (PCP76_01630)	-	329051..329812 (-)	762	Protein_313	IS3 family transposase	-
PCP76_RS01640 (PCP76_01635)	-	329804..330103 (-)	300	Protein_314	ESPR domain-containing protein	-
PCP76_RS01645 (PCP76_01640)	-	330119..331756 (-)	1638	WP_411567396.1	ShlB/FhaC/HecB family hemolysin secretion/activation protein	-
PCP76_RS01650 (PCP76_01645)	zapE	332341..333399 (+)	1059	WP_033970453.1	cell division protein ZapE	-
PCP76_RS01655 (PCP76_01650)	-	333438..334745 (-)	1308	WP_033970454.1	NAD(P)/FAD-dependent oxidoreductase	-
PCP76_RS01660 (PCP76_01655)	-	334809..334979 (-)	171	WP_003094672.1	DUF3094 family protein	-
PCP76_RS01665 (PCP76_01660)	-	335005..335454 (-)	450	WP_033970456.1	MOSC domain-containing protein	-
PCP76_RS01670 (PCP76_01665)	-	335451..336080 (-)	630	WP_003094668.1	DUF1780 domain-containing protein	-
PCP76_RS01675 (PCP76_01670)	-	336213..336638 (+)	426	WP_033976385.1	GNAT family N-acetyltransferase	-
PCP76_RS01680 (PCP76_01675)	-	336635..337105 (+)	471	WP_073649710.1	FAD/FMN-containing dehydrogenase	-

Sequence

Protein

• Length: 530 a.a.
• Molecular weight: 59116.28 Da
• Isoelectric Point: 6.4439

>NTDB_id=771602 PCP76_RS01570 WP_039028118.1 317804..319396(-) (pilS) [Pseudomonas aeruginosa strain 135]
MRAERLRLSEEQGQRILRLYHLYRLTIGLVLVLLISSELEDQVLKLVHPELFHVGSWCYLVFNILVALFLPPSRQLLPIF
ILALTDVLMLCGLFYAGGGVPSGIGSLLVVAVAIANILLRGRIGLVIAAAASLGLLYLTFFLSLSSPDATNHYVQAGGLG
TLCFAAALVIQALVRRQEQTETLAEERAETVANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQDDVQGASLG
RHSPMLMHCMKQWRLNPSLRPPTLKVLPDGPTVQPSFISLNREDDQHVLIFLEDISQIAQQAQQMKLAGLGRLTAGIAHE
IRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVDEYPGRLRND
SELHLQLGADDIQTRMDPHQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLVRDPESDLPVLEVIDDGPGVPTDKLNNLFEP
FFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFAHPRKLS

Nucleotide

• Length: 1593 bp

>NTDB_id=771602 PCP76_RS01570 WP_039028118.1 317804..319396(-) (pilS) [Pseudomonas aeruginosa strain 135]
GTGCGCGCTGAACGGCTACGGCTGAGCGAGGAGCAGGGGCAACGCATCCTCCGTCTGTACCACCTGTACCGCCTGACCAT
AGGCCTGGTACTGGTCCTGCTGATCTCCAGCGAACTGGAAGATCAGGTCCTCAAGCTCGTCCACCCTGAACTGTTCCATG
TCGGCAGTTGGTGCTACCTGGTCTTCAACATCCTGGTCGCGCTGTTCCTGCCGCCGTCGCGGCAATTGCTGCCGATCTTC
ATCCTCGCGCTCACCGACGTGCTGATGCTTTGCGGCCTGTTCTACGCAGGTGGCGGCGTGCCCAGCGGCATCGGCAGCCT
GCTGGTGGTGGCGGTGGCCATTGCCAATATCCTGCTGCGCGGGCGCATCGGCCTGGTCATCGCGGCAGCGGCCAGCCTCG
GGCTGCTCTACCTGACCTTCTTCCTCAGCCTGAGCAGCCCGGACGCCACCAACCACTACGTCCAGGCCGGCGGCCTCGGC
ACCCTGTGCTTCGCCGCCGCGCTGGTGATCCAGGCCCTGGTACGGCGCCAGGAGCAGACCGAAACGCTGGCCGAAGAACG
CGCCGAGACGGTCGCCAACCTGGAAGAACTCAACGCATTGATCCTGCAGCGTATGCGCACCGGCATCCTCGTGGTCGATA
GCCGTCAGGCCATCCTCCTCGCCAACCAGGCCGCCCTCGGCCTGCTCAGGCAGGACGACGTACAGGGCGCCAGCCTCGGC
CGCCACAGCCCGATGCTGATGCACTGCATGAAGCAATGGCGCCTGAATCCCAGCCTCCGTCCACCGACGCTCAAGGTGCT
GCCGGATGGCCCGACGGTGCAACCCAGCTTTATCAGCCTCAACCGCGAAGACGACCAGCACGTGCTGATCTTCCTCGAAG
ACATTTCGCAGATCGCCCAGCAGGCGCAGCAGATGAAGCTGGCCGGTCTCGGCCGCCTGACCGCCGGCATCGCCCATGAG
ATCCGCAACCCGCTGGGCGCGATCAGCCACGCCGCCCAGCTGCTGCAGGAGTCCGAGGAGCTGGACGCCCCGGACCGGCG
CCTGACGCAGATCATCCAGGACCAGTCGAAGCGGATGAACCTGGTCATCGAGAACGTCCTGCAGCTCTCCCGTCGCCGCC
AGGCCGAACCGCAGCAGCTCGACCTGAAGGAGTGGCTTCAGCGGTTCGTCGACGAATACCCCGGCAGGCTGCGCAACGAT
AGCGAACTGCACCTGCAACTCGGTGCCGACGACATCCAGACCCGCATGGACCCACACCAGTTGAACCAGGTGCTGAGCAA
CCTGGTGCAGAACGGCCTTCGCTACAGCGCCCAGGCGCACGGGCGCGGCCAGGTCTGGCTGAGCCTCGTGCGCGACCCGG
AGAGCGACCTGCCGGTGCTGGAAGTCATCGACGACGGTCCCGGCGTACCGACGGACAAACTGAACAACCTGTTCGAACCC
TTCTTTACTACAGAAAGCAAAGGCACCGGCCTGGGCCTCTATCTCTCCCGCGAGCTCTGCGAGAGCAACCAGGCACGGAT
CGACTACCGCAATCGCGAGGAAGGCGGCGGCTGCTTCCGCATCACCTTCGCCCACCCGCGCAAACTCAGCTGA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (310-373)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (417-523)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilS	Pseudomonas aeruginosa PAK	99.057	100	0.991