Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMY48_RS03700 Genome accession   NZ_CP127035
Coordinates   765130..765786 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain TW10573     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 760130..770786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY48_RS03665 (QMY48_00731) dcyD 761010..761996 (+) 987 WP_001297472.1 D-cysteine desulfhydrase -
  QMY48_RS03670 (QMY48_00732) tcyL 762011..762679 (+) 669 WP_001716656.1 cystine ABC transporter permease -
  QMY48_RS03675 (QMY48_00733) tcyN 762676..763428 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QMY48_RS03680 (QMY48_00734) sdiA 763658..764380 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  QMY48_RS03685 (QMY48_00735) yecF 764447..764671 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QMY48_RS03690 yecU 764658..764834 (-) 177 WP_000590347.1 protein YecU -
  QMY48_RS03695 - 764917..764988 (-) 72 Protein_721 transcriptional regulator -
  QMY48_RS03700 (QMY48_00736) letA 765130..765786 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QMY48_RS03705 (QMY48_00737) uvrC 765783..767615 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  QMY48_RS03710 (QMY48_00738) pgsA 767672..768220 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QMY48_RS03730 (QMY48_00742) yecA 768870..769535 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=770311 QMY48_RS03700 WP_000611335.1 765130..765786(+) (letA) [Escherichia coli strain TW10573]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=770311 QMY48_RS03700 WP_000611335.1 765130..765786(+) (letA) [Escherichia coli strain TW10573]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486