Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMY50_RS12535 Genome accession   NZ_CP127034
Coordinates   2336396..2337052 (+) Length   218 a.a.
NCBI ID   WP_315682356.1    Uniprot ID   -
Organism   Escherichia coli strain TW10690     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2331396..2342052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMY50_RS12500 (QMY50_02457) dcyD 2332276..2333262 (+) 987 WP_001614601.1 D-cysteine desulfhydrase -
  QMY50_RS12505 (QMY50_02458) tcyL 2333277..2333945 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QMY50_RS12510 (QMY50_02459) tcyN 2333942..2334694 (+) 753 WP_315682355.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QMY50_RS12515 (QMY50_02460) sdiA 2334924..2335646 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QMY50_RS12520 (QMY50_02461) yecF 2335713..2335937 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QMY50_RS12525 yecU 2335924..2336100 (-) 177 WP_000590344.1 protein YecU -
  QMY50_RS12530 - 2336138..2336254 (-) 117 WP_001302039.1 hypothetical protein -
  QMY50_RS12535 (QMY50_02462) letA 2336396..2337052 (+) 657 WP_315682356.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QMY50_RS12540 (QMY50_02463) uvrC 2337049..2338881 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QMY50_RS12545 (QMY50_02464) pgsA 2338938..2339486 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QMY50_RS12565 (QMY50_02468) - 2340184..2340825 (-) 642 Protein_2201 hypothetical protein -
  QMY50_RS12570 (QMY50_02469) - 2340834..2341739 (-) 906 Protein_2202 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23888.71 Da        Isoelectric Point: 6.9614

>NTDB_id=770272 QMY50_RS12535 WP_315682356.1 2336396..2337052(+) (letA) [Escherichia coli strain TW10690]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLLSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=770272 QMY50_RS12535 WP_315682356.1 2336396..2337052(+) (letA) [Escherichia coli strain TW10690]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATTAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

49.541

100

0.495
  letA Legionella pneumophila strain ERS1305867

49.541

100

0.495