Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   F6I26_RS07765 Genome accession   NZ_CP126961
Coordinates   1533092..1534882 (-) Length   596 a.a.
NCBI ID   WP_024053005.1    Uniprot ID   A0A412PNC4
Organism   Streptococcus anginosus strain UMB4708     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1528092..1539882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I26_RS07735 (F6I26_007735) - 1528883..1529335 (-) 453 WP_006268509.1 MarR family transcriptional regulator -
  F6I26_RS07740 (F6I26_007740) - 1529437..1530021 (-) 585 WP_024053010.1 uracil-DNA glycosylase family protein -
  F6I26_RS07745 (F6I26_007745) - 1530031..1530213 (-) 183 WP_024053009.1 NmrA family protein -
  F6I26_RS07750 (F6I26_007750) - 1530217..1530888 (-) 672 WP_024053008.1 NmrA family NAD(P)-binding protein -
  F6I26_RS07755 (F6I26_007755) pepV 1530944..1532344 (-) 1401 WP_024053007.1 dipeptidase PepV -
  F6I26_RS07760 (F6I26_007760) - 1532364..1532969 (-) 606 WP_024053006.1 nitroreductase family protein -
  F6I26_RS07765 (F6I26_007765) uvrC 1533092..1534882 (-) 1791 WP_024053005.1 excinuclease ABC subunit UvrC Machinery gene
  F6I26_RS07770 (F6I26_007770) ptsP 1535033..1536766 (-) 1734 WP_024053004.1 phosphoenolpyruvate--protein phosphotransferase -
  F6I26_RS07775 (F6I26_007775) - 1536768..1537031 (-) 264 WP_003023815.1 phosphocarrier protein HPr -
  F6I26_RS07780 (F6I26_007780) nrdH 1537429..1537647 (+) 219 WP_003023812.1 glutaredoxin-like protein NrdH -

Sequence

Protein


Download         Length: 596 a.a.        Molecular weight: 68682.29 Da        Isoelectric Point: 9.5992

>NTDB_id=769560 F6I26_RS07765 WP_024053005.1 1533092..1534882(-) (uvrC) [Streptococcus anginosus strain UMB4708]
MNNLIKSKLELLPTSPGCYIHKDKNGIIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIEDFEFIVTESNIEALLLEIN
LIKENRPKYNIMLKDDKSYPFIKITNEIYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPEKVCF
YYHIGQCRAHTVCHNDPHFFQEMAQEVADFLKGHDNKIIDELKGKMTSAAEKMEFEKAAEYRNLLQSIATLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNMFPYYNDPDEDFLTYIGQFYQEKSHLIPNEILIPSDIDEIAVQAV
VDTKILKPQRGEKKQLVNLAIKNAQVSLQQKFDLLEKSVEKTQGAIENLGQLLNIPTPVRIESFDNSNIMGTSPVSAMVV
FINGKPSKKDYRKYKIKTVIGPDDYASMREVIKRRYSRVMRDGLIPPDLIVIDGGQGQVNIAKDVIQNQLGLDIPIAGLQ
KNDKHQTHELLFGDPLKVVELSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIEGLGPKRKQNLMRHFKSL
ANIKKASVDEIVEVGVPRKVAEAVQRKLRESRDKKE

Nucleotide


Download         Length: 1791 bp        

>NTDB_id=769560 F6I26_RS07765 WP_024053005.1 1533092..1534882(-) (uvrC) [Streptococcus anginosus strain UMB4708]
ATGAACAACTTGATTAAATCAAAATTAGAATTGTTGCCTACTAGTCCAGGTTGCTATATTCATAAAGATAAAAATGGCAT
TATCATCTATGTCGGAAAAGCTAAGAATCTGCGTAATCGGGTGCGCTCTTATTTTCGTGGGAGCCATGATACTAAAACGG
AAGCACTGGTGTCTGAGATTGAGGATTTTGAGTTTATTGTCACGGAGTCTAATATTGAAGCCTTGCTGCTTGAAATCAAT
CTAATCAAGGAAAATCGGCCTAAATATAACATCATGCTTAAGGACGATAAGTCCTATCCTTTTATCAAAATCACCAATGA
GATATATCCGCGACTTATTATTACACGTCAGGTTAAAAAAGATGGTGGTTTATATTTTGGCCCGTATCCTGATGTAGGTG
CTGCGAATGAAATTAAGCGCCTGCTGGATCGCATTTTTCCTTTCCGCAAGTGTACCAATCCACCTGAGAAAGTTTGCTTC
TACTATCATATCGGACAGTGTCGAGCTCATACTGTCTGCCATAATGATCCACATTTCTTTCAAGAGATGGCTCAAGAAGT
AGCAGATTTCCTCAAAGGTCATGATAATAAGATTATTGATGAATTGAAAGGAAAAATGACTAGTGCTGCTGAAAAGATGG
AATTTGAAAAAGCGGCTGAATACCGAAATTTGCTTCAAAGTATTGCGACACTTCGCACCAAGCAACGAGTGATGGCAAAG
GATTTACAGAATCGGGATGTCTTTGGCTATTATGTGGACAAAGGATGGATGTGTGTACAGGTTTTCTTTGTCCGTCAAGG
AAAACTCATTGAGCGAGATGTAAATATGTTTCCTTATTACAATGACCCTGACGAGGATTTTCTGACCTATATTGGTCAAT
TTTATCAGGAAAAATCTCATCTGATTCCCAATGAAATTTTGATTCCATCTGATATTGATGAAATAGCTGTTCAGGCTGTG
GTGGATACGAAGATTCTCAAACCTCAGCGAGGAGAGAAGAAACAGCTGGTTAATTTGGCTATTAAAAATGCGCAAGTTAG
TTTGCAGCAGAAGTTTGATTTGTTGGAGAAATCTGTTGAAAAAACACAGGGAGCTATTGAAAATCTAGGTCAGTTGCTCA
ATATTCCCACTCCAGTTCGGATTGAATCGTTTGATAATTCCAATATTATGGGAACAAGTCCTGTTTCAGCTATGGTGGTT
TTTATCAATGGCAAACCCAGCAAAAAAGATTATCGCAAGTATAAGATTAAGACAGTTATCGGTCCTGATGACTATGCTAG
TATGCGAGAAGTGATTAAGCGCCGTTACAGTCGGGTTATGCGAGATGGTTTAATACCGCCTGATCTTATTGTCATTGACG
GTGGTCAGGGTCAAGTCAATATTGCTAAAGACGTCATTCAAAATCAATTAGGGTTAGATATTCCTATCGCTGGTTTGCAA
AAAAATGACAAGCACCAGACGCATGAATTGCTCTTTGGCGATCCTTTGAAAGTGGTTGAGTTATCTCGCAATTCGCAGGA
ATTTTTCCTCTTACAACGCATTCAAGATGAGGTGCACCGCTTTGCCATTACCTTCCACCGCCAGCTTCGCTCAAAAAACT
CCTTTTCTTCGCAACTAGATGGCATTGAAGGACTGGGGCCTAAACGCAAGCAAAATCTGATGCGACATTTTAAATCTTTG
GCTAATATCAAGAAAGCTAGTGTTGATGAAATTGTCGAAGTGGGTGTACCGCGAAAAGTGGCAGAGGCAGTGCAGAGAAA
ATTGAGAGAGTCTAGAGATAAAAAAGAATAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(197-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

Helix-hairpin-helix domain (HHH_5)

(538-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PNC4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

89.456

98.658

0.883
  uvrC Streptococcus pneumoniae TIGR4

89.456

98.658

0.883
  uvrC Streptococcus pneumoniae D39

89.456

98.658

0.883