Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA21_RS12555 Genome accession   NZ_CP126955
Coordinates   2510526..2511182 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O78:H4 strain APEC E123     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2505526..2516182
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA21_RS12525 (QQA21_12525) yecA 2506777..2507442 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  QQA21_RS12545 (QQA21_12545) pgsA 2508092..2508640 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA21_RS12550 (QQA21_12550) uvrC 2508697..2510529 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQA21_RS12555 (QQA21_12555) letA 2510526..2511182 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA21_RS25660 - 2511324..2511440 (+) 117 Protein_2466 transcriptional regulator -
  QQA21_RS12560 (QQA21_12560) yecU 2511478..2511654 (+) 177 WP_000590344.1 protein YecU -
  QQA21_RS12565 (QQA21_12565) yecF 2511641..2511865 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA21_RS12570 (QQA21_12570) sdiA 2511933..2512655 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  QQA21_RS12575 (QQA21_12575) tcyN 2512885..2513637 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA21_RS12580 (QQA21_12580) tcyL 2513634..2514302 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA21_RS12585 (QQA21_12585) dcyD 2514317..2515303 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=769432 QQA21_RS12555 WP_000611335.1 2510526..2511182(-) (letA) [Escherichia coli O78:H4 strain APEC E123]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=769432 QQA21_RS12555 WP_000611335.1 2510526..2511182(-) (letA) [Escherichia coli O78:H4 strain APEC E123]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486