Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA22_RS09980 Genome accession   NZ_CP126952
Coordinates   2086174..2086830 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O78:H4 strain APEC E12049     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2081174..2091830
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA22_RS09950 (QQA22_09950) dcyD 2082054..2083040 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QQA22_RS09955 (QQA22_09955) tcyL 2083055..2083723 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA22_RS09960 (QQA22_09960) tcyN 2083720..2084472 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA22_RS09965 (QQA22_09965) sdiA 2084702..2085424 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QQA22_RS09970 (QQA22_09970) yecF 2085491..2085715 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA22_RS09975 (QQA22_09975) yecU 2085702..2085878 (-) 177 WP_000590344.1 protein YecU -
  QQA22_RS26640 - 2085916..2086032 (-) 117 WP_001302039.1 hypothetical protein -
  QQA22_RS09980 (QQA22_09980) letA 2086174..2086830 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA22_RS09985 (QQA22_09985) uvrC 2086827..2088659 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  QQA22_RS09990 (QQA22_09990) pgsA 2088716..2089264 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA22_RS10010 (QQA22_10010) yecA 2089914..2090579 (+) 666 WP_000847885.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=769358 QQA22_RS09980 WP_000611335.1 2086174..2086830(+) (letA) [Escherichia coli O78:H4 strain APEC E12049]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=769358 QQA22_RS09980 WP_000611335.1 2086174..2086830(+) (letA) [Escherichia coli O78:H4 strain APEC E12049]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486