Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA24_RS12510 Genome accession   NZ_CP126946
Coordinates   2559453..2560109 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O78:H51 strain APEC E18005     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2554453..2565109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA24_RS12480 (QQA24_12480) yecA 2555704..2556369 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  QQA24_RS12500 (QQA24_12500) pgsA 2557019..2557567 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA24_RS12505 (QQA24_12505) uvrC 2557624..2559456 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQA24_RS12510 (QQA24_12510) letA 2559453..2560109 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA24_RS26145 - 2560251..2560367 (+) 117 WP_001302039.1 hypothetical protein -
  QQA24_RS12515 (QQA24_12515) yecU 2560405..2560581 (+) 177 WP_000590344.1 protein YecU -
  QQA24_RS12520 (QQA24_12520) yecF 2560568..2560792 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA24_RS12525 (QQA24_12525) sdiA 2560860..2561582 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  QQA24_RS12530 (QQA24_12530) tcyN 2561812..2562564 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA24_RS12535 (QQA24_12535) tcyL 2562561..2563229 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA24_RS12540 (QQA24_12540) dcyD 2563244..2564230 (-) 987 WP_001724631.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=769182 QQA24_RS12510 WP_000611335.1 2559453..2560109(-) (letA) [Escherichia coli O78:H51 strain APEC E18005]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=769182 QQA24_RS12510 WP_000611335.1 2559453..2560109(-) (letA) [Escherichia coli O78:H51 strain APEC E18005]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486