Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA29_RS10890 Genome accession   NZ_CP126942
Coordinates   2228445..2229101 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O1:K1:H7 strain APEC E18006     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2223445..2234101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA29_RS10860 (QQA29_10860) dcyD 2224324..2225310 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  QQA29_RS10865 (QQA29_10865) tcyL 2225325..2225993 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA29_RS10870 (QQA29_10870) tcyN 2225990..2226742 (+) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA29_RS10875 (QQA29_10875) sdiA 2226972..2227694 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  QQA29_RS10880 (QQA29_10880) yecF 2227762..2227986 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA29_RS10885 (QQA29_10885) yecU 2227973..2228149 (-) 177 WP_001307856.1 protein YecU -
  QQA29_RS10890 (QQA29_10890) letA 2228445..2229101 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA29_RS10895 (QQA29_10895) uvrC 2229098..2230930 (+) 1833 WP_001283434.1 excinuclease ABC subunit UvrC Machinery gene
  QQA29_RS10900 (QQA29_10900) pgsA 2230987..2231535 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA29_RS10920 (QQA29_10920) yecA 2232185..2232850 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=769018 QQA29_RS10890 WP_000611328.1 2228445..2229101(+) (letA) [Escherichia coli O1:K1:H7 strain APEC E18006]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=769018 QQA29_RS10890 WP_000611328.1 2228445..2229101(+) (letA) [Escherichia coli O1:K1:H7 strain APEC E18006]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482