Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA31_RS10105 Genome accession   NZ_CP126937
Coordinates   2103050..2103706 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O2:K1:H4 strain APEC E19019     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2098050..2108706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA31_RS10075 (QQA31_10075) dcyD 2098930..2099916 (+) 987 WP_001128222.1 D-cysteine desulfhydrase -
  QQA31_RS10080 (QQA31_10080) tcyL 2099931..2100599 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA31_RS10085 (QQA31_10085) tcyN 2100596..2101348 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA31_RS10090 (QQA31_10090) sdiA 2101578..2102300 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QQA31_RS10095 (QQA31_10095) yecF 2102367..2102591 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA31_RS10100 (QQA31_10100) yecU 2102578..2102754 (-) 177 WP_001326718.1 protein YecU -
  QQA31_RS25400 - 2102837..2102908 (-) 72 Protein_1976 transcriptional regulator -
  QQA31_RS10105 (QQA31_10105) letA 2103050..2103706 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA31_RS10110 (QQA31_10110) uvrC 2103703..2105535 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQA31_RS10115 (QQA31_10115) pgsA 2105592..2106140 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA31_RS10135 (QQA31_10135) yecA 2106790..2107455 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=768847 QQA31_RS10105 WP_000611335.1 2103050..2103706(+) (letA) [Escherichia coli O2:K1:H4 strain APEC E19019]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=768847 QQA31_RS10105 WP_000611335.1 2103050..2103706(+) (letA) [Escherichia coli O2:K1:H4 strain APEC E19019]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486