Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QQA26_RS08145 Genome accession   NZ_CP126934
Coordinates   1598040..1598696 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O78:H4 strain APEC E19057     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1593040..1603696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QQA26_RS08115 (QQA26_08115) yecA 1594291..1594956 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  QQA26_RS08135 (QQA26_08135) pgsA 1595606..1596154 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QQA26_RS08140 (QQA26_08140) uvrC 1596211..1598043 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QQA26_RS08145 (QQA26_08145) letA 1598040..1598696 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QQA26_RS25265 - 1598838..1598954 (+) 117 Protein_1605 transcriptional regulator -
  QQA26_RS08150 (QQA26_08150) yecU 1598992..1599168 (+) 177 WP_000590344.1 protein YecU -
  QQA26_RS08155 (QQA26_08155) yecF 1599155..1599379 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  QQA26_RS08160 (QQA26_08160) sdiA 1599447..1600169 (-) 723 WP_001152713.1 transcriptional regulator SdiA -
  QQA26_RS08165 (QQA26_08165) tcyN 1600399..1601151 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QQA26_RS08170 (QQA26_08170) tcyL 1601148..1601816 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  QQA26_RS08175 (QQA26_08175) dcyD 1601831..1602817 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=768741 QQA26_RS08145 WP_000611335.1 1598040..1598696(-) (letA) [Escherichia coli O78:H4 strain APEC E19057]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=768741 QQA26_RS08145 WP_000611335.1 1598040..1598696(-) (letA) [Escherichia coli O78:H4 strain APEC E19057]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486