Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   LLE01_RS09690 Genome accession   NZ_CP126675
Coordinates   1705819..1707054 (+) Length   411 a.a.
NCBI ID   WP_010905787.1    Uniprot ID   Q9CGE6
Organism   Lactococcus lactis subsp. lactis strain E.0.1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1700819..1712054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLE01_RS09665 (LLE01_09640) - 1701653..1702246 (+) 594 WP_003132093.1 xanthine phosphoribosyltransferase -
  LLE01_RS09670 (LLE01_09645) - 1702295..1703599 (+) 1305 WP_003132095.1 nucleobase:cation symporter-2 family protein -
  LLE01_RS09675 (LLE01_09650) - 1703628..1704041 (-) 414 WP_003132097.1 hypothetical protein -
  LLE01_RS09680 (LLE01_09655) - 1704161..1704670 (-) 510 WP_010905785.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  LLE01_RS09685 (LLE01_09660) - 1705069..1705575 (+) 507 WP_010905786.1 dihydrofolate reductase -
  LLE01_RS09690 (LLE01_09665) clpX 1705819..1707054 (+) 1236 WP_010905787.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  LLE01_RS09695 (LLE01_09670) yihA 1707051..1707638 (+) 588 WP_010905788.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  LLE01_RS09700 (LLE01_09675) folB 1707692..1708042 (+) 351 WP_003132106.1 dihydroneopterin aldolase -
  LLE01_RS09705 (LLE01_09680) folE 1708122..1709171 (+) 1050 WP_010905789.1 GTP cyclohydrolase I FolE -
  LLE01_RS09710 (LLE01_09685) folP 1709168..1710241 (+) 1074 WP_003132109.1 dihydropteroate synthase -
  LLE01_RS09715 (LLE01_09690) - 1710244..1710741 (+) 498 WP_003132112.1 NUDIX domain-containing protein -
  LLE01_RS09720 (LLE01_09695) - 1710760..1712043 (+) 1284 WP_003132113.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 45976.83 Da        Isoelectric Point: 4.6053

>NTDB_id=768098 LLE01_RS09690 WP_010905787.1 1705819..1707054(+) (clpX) [Lactococcus lactis subsp. lactis strain E.0.1]
MSNTQNPNIHCSFCGKSQDDVKKLIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=768098 LLE01_RS09690 WP_010905787.1 1705819..1707054(+) (clpX) [Lactococcus lactis subsp. lactis strain E.0.1]
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGTGGAAAGAGTCAAGATGATGTAAAAAAATTGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAATATGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTGCAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAATATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ACGTTCCATTTGCGATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GAACGGTAGCTAGTGTTCCACCACAAGGTGGACGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATTGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGATTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTCGGATTAA
TTCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAACGTTTGACCGAAGAGGATTTGATTCAAATTTTGACA
GAACCTAAAAATGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAAGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Domains

Predicted by InterProScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(10-46)

AAA domain (Cdc48 subfamily) (AAA_2)

(108-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(310-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CGE6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

76.559

97.567

0.747
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.883

95.864

0.564