Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   QPR37_RS08585 Genome accession   NZ_CP126631
Coordinates   1719894..1721156 (+) Length   420 a.a.
NCBI ID   WP_000472293.1    Uniprot ID   Q6GG31
Organism   Staphylococcus aureus strain 33-40     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1714894..1726156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPR37_RS08550 (QPR37_08550) infC 1715422..1715949 (+) 528 WP_001791162.1 translation initiation factor IF-3 -
  QPR37_RS08555 (QPR37_08555) rpmI 1715978..1716178 (+) 201 WP_001125540.1 50S ribosomal protein L35 -
  QPR37_RS08560 (QPR37_08560) rplT 1716225..1716581 (+) 357 WP_001138360.1 50S ribosomal protein L20 -
  QPR37_RS08565 (QPR37_08565) - 1716723..1717331 (+) 609 WP_000032657.1 NUDIX domain-containing protein -
  QPR37_RS08570 (QPR37_08570) - 1717350..1718279 (+) 930 WP_063651435.1 hypothetical protein -
  QPR37_RS08575 (QPR37_08575) - 1718284..1718394 (+) 111 WP_001790560.1 hypothetical protein -
  QPR37_RS08580 (QPR37_08580) tig 1718442..1719743 (+) 1302 WP_000127572.1 trigger factor -
  QPR37_RS08585 (QPR37_08585) clpX 1719894..1721156 (+) 1263 WP_000472293.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  QPR37_RS08590 (QPR37_08590) yihA 1721310..1721900 (+) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  QPR37_RS08595 (QPR37_08595) hemA 1722117..1723463 (+) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  QPR37_RS08600 (QPR37_08600) - 1723485..1724300 (+) 816 WP_001157329.1 cytochrome c biogenesis protein -
  QPR37_RS08605 (QPR37_08605) hemC 1724342..1725268 (+) 927 WP_001230225.1 hydroxymethylbilane synthase -
  QPR37_RS08610 (QPR37_08610) - 1725290..1725958 (+) 669 WP_063651430.1 uroporphyrinogen-III synthase -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46279.44 Da        Isoelectric Point: 4.2645

>NTDB_id=767989 QPR37_RS08585 WP_000472293.1 1719894..1721156(+) (clpX) [Staphylococcus aureus strain 33-40]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=767989 QPR37_RS08585 WP_000472293.1 1719894..1721156(+) (clpX) [Staphylococcus aureus strain 33-40]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATAGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
GTTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTA
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGAACAACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCAT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAATTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6GG31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531