Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F0313_RS01145 Genome accession   NZ_CP126600
Coordinates   217259..217915 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain Ec1119     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 212259..222915
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F0313_RS01110 (F0313_001105) dcyD 213139..214125 (+) 987 WP_001128204.1 D-cysteine desulfhydrase -
  F0313_RS01115 (F0313_001110) tcyL 214140..214808 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  F0313_RS01120 (F0313_001115) tcyN 214805..215557 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  F0313_RS01125 (F0313_001120) sdiA 215787..216509 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  F0313_RS01130 (F0313_001125) yecF 216576..216800 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  F0313_RS01135 (F0313_001130) yecU 216787..216963 (-) 177 WP_000590347.1 protein YecU -
  F0313_RS01140 - 217046..217117 (-) 72 Protein_222 transcriptional regulator -
  F0313_RS01145 (F0313_001135) letA 217259..217915 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  F0313_RS01150 (F0313_001140) uvrC 217912..219744 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  F0313_RS01155 (F0313_001145) pgsA 219801..220349 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  F0313_RS01175 (F0313_001165) yecA 220999..221664 (+) 666 WP_149488457.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=767635 F0313_RS01145 WP_000611335.1 217259..217915(+) (letA) [Escherichia coli strain Ec1119]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=767635 F0313_RS01145 WP_000611335.1 217259..217915(+) (letA) [Escherichia coli strain Ec1119]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486