Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   O6U12_RS00525 Genome accession   NZ_CP114899
Coordinates   107522..108166 (+) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 102522..113166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6U12_RS00495 (O6U12_00495) - 102872..103240 (-) 369 WP_017695529.1 hypothetical protein -
  O6U12_RS00500 (O6U12_00500) - 103418..103480 (-) 63 Protein_100 hypothetical protein -
  O6U12_RS00505 (O6U12_00505) degQ 103702..103842 (+) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  O6U12_RS00510 (O6U12_00510) - 104027..104890 (+) 864 WP_014480705.1 polyprenyl synthetase family protein -
  O6U12_RS00515 (O6U12_00515) comX 104892..105113 (+) 222 WP_014480704.1 competence pheromone ComX -
  O6U12_RS00520 (O6U12_00520) comP 105129..107441 (+) 2313 WP_014480703.1 sensor histidine kinase Regulator
  O6U12_RS00525 (O6U12_00525) comA 107522..108166 (+) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  O6U12_RS00530 (O6U12_00530) yuxO 108185..108565 (+) 381 WP_017695528.1 hotdog fold thioesterase -
  O6U12_RS00535 (O6U12_00535) mnhG 108604..108978 (-) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  O6U12_RS00540 (O6U12_00540) mrpF 108962..109246 (-) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  O6U12_RS00545 (O6U12_00545) mrpE 109246..109722 (-) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  O6U12_RS00550 (O6U12_00550) mrpD 109728..111209 (-) 1482 WP_017695527.1 Na+/H+ antiporter subunit D -
  O6U12_RS00555 (O6U12_00555) mrpC 111202..111543 (-) 342 WP_014480700.1 Na(+)/H(+) antiporter subunit C -
  O6U12_RS00560 (O6U12_00560) mrpB 111543..111974 (-) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=767558 O6U12_RS00525 WP_003220716.1 107522..108166(+) (comA) [Bacillus subtilis strain]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=767558 O6U12_RS00525 WP_003220716.1 107522..108166(+) (comA) [Bacillus subtilis strain]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATTT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATCTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAAGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTTAATAAGCTGAATGTCGGTTCACGGACGGAAGCGGTTTTGATAGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1