Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   LL303_RS06395 Genome accession   NZ_CP126467
Coordinates   1211195..1212430 (+) Length   411 a.a.
NCBI ID   WP_014570582.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain 303     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1206195..1217430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL303_RS06370 (LL303_06365) - 1207029..1207622 (+) 594 WP_003132093.1 xanthine phosphoribosyltransferase -
  LL303_RS06375 (LL303_06370) - 1207671..1208975 (+) 1305 WP_003132095.1 nucleobase:cation symporter-2 family protein -
  LL303_RS06380 (LL303_06375) - 1209004..1209417 (-) 414 WP_003132097.1 hypothetical protein -
  LL303_RS06385 (LL303_06380) - 1209537..1210046 (-) 510 WP_010905785.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  LL303_RS06390 (LL303_06385) - 1210445..1210951 (+) 507 WP_010905786.1 dihydrofolate reductase -
  LL303_RS06395 (LL303_06390) clpX 1211195..1212430 (+) 1236 WP_014570582.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  LL303_RS06400 (LL303_06395) yihA 1212427..1213014 (+) 588 WP_023164083.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  LL303_RS06405 (LL303_06400) folB 1213068..1213418 (+) 351 WP_003132106.1 dihydroneopterin aldolase -
  LL303_RS06410 (LL303_06405) folE 1213498..1214547 (+) 1050 WP_014570583.1 GTP cyclohydrolase I FolE -
  LL303_RS06415 (LL303_06410) folP 1214544..1215617 (+) 1074 WP_003132109.1 dihydropteroate synthase -
  LL303_RS06420 (LL303_06415) - 1215620..1216117 (+) 498 WP_003132112.1 NUDIX domain-containing protein -
  LL303_RS06425 (LL303_06420) - 1216136..1217419 (+) 1284 WP_031559471.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 45994.86 Da        Isoelectric Point: 4.6053

>NTDB_id=767348 LL303_RS06395 WP_014570582.1 1211195..1212430(+) (clpX) [Lactococcus lactis subsp. lactis strain 303]
MSNTQNPNIHCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFAASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=767348 LL303_RS06395 WP_014570582.1 1211195..1212430(+) (clpX) [Lactococcus lactis subsp. lactis strain 303]
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGTGGAAAGAGTCAAGACGATGTAAAAAAAATGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAATATGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTGCAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAATATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ACGTTCCATTTGCGATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GAACGGTAGCTAGTGTTCCACCACAAGGTGGACGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATTGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGATTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTCGGATTAA
TTCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAACGTTTGACCGAAGAGGATTTGATTCAAATTTTGACA
GAACCTAAAAATGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAAGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(108-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(10-46)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(310-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

76.559

97.567

0.747
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.883

95.864

0.564