Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   O6R09_RS02145 Genome accession   NZ_CP114883
Coordinates   393968..395266 (+) Length   432 a.a.
NCBI ID   WP_269725724.1    Uniprot ID   -
Organism   Streptococcus alactolyticus strain LGM     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 388968..400266
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  O6R09_RS02120 (O6R09_02120) - 389688..390332 (+) 645 WP_154454637.1 response regulator transcription factor -
  O6R09_RS02125 (O6R09_02125) - 390413..391816 (+) 1404 WP_269725723.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  O6R09_RS02130 (O6R09_02130) - 391813..392172 (+) 360 WP_154454635.1 S1 RNA-binding domain-containing protein -
  O6R09_RS02135 (O6R09_02135) cysK 392259..393188 (-) 930 WP_154454634.1 cysteine synthase A -
  O6R09_RS02140 (O6R09_02140) - 393286..393912 (-) 627 WP_154454633.1 YigZ family protein -
  O6R09_RS02145 (O6R09_02145) comFA/cflA 393968..395266 (+) 1299 WP_269725724.1 DEAD/DEAH box helicase Machinery gene
  O6R09_RS02150 (O6R09_02150) - 395266..395928 (+) 663 WP_235280525.1 ComF family protein -
  O6R09_RS02155 (O6R09_02155) hpf 396009..396557 (+) 549 WP_235280528.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 48993.27 Da        Isoelectric Point: 9.9166

>NTDB_id=767321 O6R09_RS02145 WP_269725724.1 393968..395266(+) (comFA/cflA) [Streptococcus alactolyticus strain LGM]
MNSLEYYYGRLFTSEQLTDALKKQAKALPAMIDHKTHAECCRCGSKVFSNYQLQTGALYCRECLVFGRNTNQQSLYYFPQ
KPFPKEDVLVWKGQLTPYQENISQGMLKAIAAKKDLLVHAVTGAGKTEMIYHAIATVIANGGCVGLASPRIDVCLELYKR
LSQDFACKISLLYGGSEKYQRAPLVISTTHQLLKFYQAFDLLIIDEVDVFPFVDNHMLYHAVEQSLKKEGSKIYLTATST
DQLDKQVQSGKLAKLHLPRRFHANPLVVPKNIWLSGVLKHMQKGQLPRAFMKILTKQRQTKYPLLIFFPNIAQGQVFTKI
LKTYLPHENIAFVSSQTENRLEIVNQFRQQELSILVTTTILERGVTFPCVDVFVMLAHHRLYTKSALVQISGRVGRAKER
PTGALLFLHEGITKPMTKAIAEIKEMNKRGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=767321 O6R09_RS02145 WP_269725724.1 393968..395266(+) (comFA/cflA) [Streptococcus alactolyticus strain LGM]
ATGAACTCATTAGAATACTATTATGGAAGATTATTTACTTCAGAACAATTAACAGATGCCTTAAAAAAGCAGGCTAAGGC
TCTTCCCGCTATGATAGATCACAAGACTCATGCAGAGTGTTGTCGTTGTGGCAGCAAGGTTTTCTCGAATTACCAATTAC
AAACAGGAGCCTTGTATTGTCGAGAATGTCTGGTTTTTGGACGAAATACAAATCAGCAGTCCTTGTATTATTTCCCACAA
AAGCCATTTCCAAAAGAAGATGTTTTGGTTTGGAAGGGTCAATTAACCCCTTATCAAGAAAATATATCGCAAGGCATGTT
GAAAGCTATCGCGGCTAAAAAAGATTTATTGGTCCATGCCGTAACAGGGGCAGGTAAGACAGAGATGATTTACCACGCTA
TTGCGACCGTGATTGCTAATGGTGGTTGTGTTGGATTAGCCAGCCCTCGAATTGATGTATGCCTTGAATTGTACAAGCGT
CTGTCACAAGATTTTGCTTGTAAGATTAGTTTGCTGTATGGAGGATCCGAAAAATACCAACGTGCTCCACTAGTGATTTC
AACAACTCATCAATTATTGAAATTCTATCAAGCCTTTGATTTGTTGATTATTGATGAAGTGGACGTCTTTCCCTTTGTGG
ATAATCATATGTTGTATCACGCAGTCGAGCAATCGCTCAAAAAAGAAGGGAGCAAGATTTACCTCACAGCCACCTCCACA
GACCAGTTGGACAAACAGGTGCAAAGCGGTAAATTAGCTAAGCTGCATTTACCTAGACGATTTCATGCGAATCCTCTCGT
CGTTCCCAAAAACATTTGGCTGAGTGGTGTTTTAAAGCACATGCAAAAAGGCCAACTTCCTAGAGCCTTCATGAAAATCT
TGACAAAACAGCGTCAGACTAAGTATCCCTTACTCATCTTTTTTCCAAATATCGCACAAGGTCAGGTATTTACAAAGATT
TTAAAAACGTATTTGCCACACGAAAATATCGCTTTTGTGTCCAGTCAGACGGAAAACCGTTTGGAAATCGTCAATCAATT
TAGGCAGCAAGAGTTATCGATTTTAGTGACAACAACGATTTTGGAGCGAGGGGTGACCTTTCCTTGTGTGGACGTTTTTG
TTATGCTAGCCCACCATCGCCTATACACCAAAAGTGCCCTCGTGCAAATTTCTGGGCGTGTCGGTCGTGCCAAGGAGCGT
CCGACAGGCGCACTATTATTTTTACATGAAGGCATTACGAAACCAATGACTAAGGCAATTGCTGAAATTAAAGAAATGAA
TAAAAGAGGTGGTTTTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(105-244)

Helicase conserved C-terminal domain (Helicase_C)

(287-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.624

98.611

0.588
  comFA/cflA Streptococcus pneumoniae D39

59.624

98.611

0.588
  comFA/cflA Streptococcus pneumoniae R6

59.624

98.611

0.588
  comFA/cflA Streptococcus mitis SK321

59.39

98.611

0.586
  comFA/cflA Streptococcus pneumoniae TIGR4

59.39

98.611

0.586
  comFA/cflA Streptococcus mitis NCTC 12261

59.155

98.611

0.583
  comFA Lactococcus lactis subsp. cremoris KW2

51.015

91.204

0.465
  comFA Latilactobacillus sakei subsp. sakei 23K

38.747

99.769

0.387