Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QN227_RS08935 Genome accession   NZ_CP126348
Coordinates   1873572..1874228 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain NN5     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1868572..1879228
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN227_RS08905 (QN227_08905) dcyD 1869452..1870438 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QN227_RS08910 (QN227_08910) tcyL 1870453..1871121 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QN227_RS08915 (QN227_08915) tcyN 1871118..1871870 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QN227_RS08920 (QN227_08920) sdiA 1872100..1872822 (+) 723 WP_033557521.1 transcriptional regulator SdiA -
  QN227_RS08925 (QN227_08925) yecF 1872889..1873113 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QN227_RS08930 (QN227_08930) yecU 1873100..1873276 (-) 177 WP_000590347.1 protein YecU -
  QN227_RS22370 - 1873359..1873430 (-) 72 Protein_1742 transcriptional regulator -
  QN227_RS08935 (QN227_08935) letA 1873572..1874228 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QN227_RS08940 (QN227_08940) uvrC 1874225..1876057 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QN227_RS08945 (QN227_08945) pgsA 1876114..1876662 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QN227_RS08965 (QN227_08965) yecA 1877311..1877976 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=767272 QN227_RS08935 WP_000611335.1 1873572..1874228(+) (letA) [Escherichia coli strain NN5]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=767272 QN227_RS08935 WP_000611335.1 1873572..1874228(+) (letA) [Escherichia coli strain NN5]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486