Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QMW19_RS09760 Genome accession   NZ_CP125731
Coordinates   2021597..2022253 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GYB01     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2016597..2027253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMW19_RS09730 (QMW19_09730) dcyD 2017476..2018462 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QMW19_RS09735 (QMW19_09735) tcyL 2018477..2019145 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QMW19_RS09740 (QMW19_09740) tcyN 2019142..2019894 (+) 753 WP_001272990.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QMW19_RS09745 (QMW19_09745) sdiA 2020124..2020846 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  QMW19_RS09750 (QMW19_09750) yecF 2020914..2021138 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QMW19_RS09755 (QMW19_09755) yecU 2021125..2021301 (-) 177 WP_001302050.1 protein YecU -
  QMW19_RS25175 - 2021339..2021455 (-) 117 WP_001302039.1 hypothetical protein -
  QMW19_RS09760 (QMW19_09760) letA 2021597..2022253 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QMW19_RS09765 (QMW19_09765) uvrC 2022250..2024082 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QMW19_RS09770 (QMW19_09770) pgsA 2024139..2024687 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QMW19_RS09790 (QMW19_09790) yecA 2025337..2026002 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=763590 QMW19_RS09760 WP_000611328.1 2021597..2022253(+) (letA) [Escherichia coli strain GYB01]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=763590 QMW19_RS09760 WP_000611328.1 2021597..2022253(+) (letA) [Escherichia coli strain GYB01]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482