Detailed information NTG0762550

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: OPT59_RS10965
• Genome accession: NZ_CP125360
• Coordinates: 2219824..2222379 (-)
• Length: 851 a.a.
• NCBI ID: WP_003061429.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain UT_120444
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2214824..2227379

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OPT59_RS10945 (OPT59_10945)	-	2215317..2215877 (-)	561	WP_011018314.1	DNA-3-methyladenine glycosylase I	-
OPT59_RS10950 (OPT59_10950)	ruvA	2215887..2216483 (-)	597	WP_015017499.1	Holliday junction branch migration protein RuvA	Machinery gene
OPT59_RS10955 (OPT59_10955)	-	2216485..2217705 (-)	1221	WP_003058727.1	MFS transporter	-
OPT59_RS10960 (OPT59_10960)	hexB	2217716..2219698 (-)	1983	WP_003060855.1	DNA mismatch repair endonuclease MutL	Machinery gene
OPT59_RS10965 (OPT59_10965)	hexA	2219824..2222379 (-)	2556	WP_003061429.1	DNA mismatch repair protein MutS	Machinery gene
OPT59_RS10970 (OPT59_10970)	-	2222366..2222719 (-)	354	WP_003062220.1	YlbF family regulator	-
OPT59_RS10975 (OPT59_10975)	argR	2222716..2223153 (-)	438	WP_003055516.1	arginine repressor	-
OPT59_RS10980 (OPT59_10980)	argS	2223442..2225133 (+)	1692	WP_015017500.1	arginine--tRNA ligase	-
OPT59_RS10985 (OPT59_10985)	-	2225203..2226600 (-)	1398	WP_014612639.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95312.77 Da
• Isoelectric Point: 4.8806

>NTDB_id=762550 OPT59_RS10965 WP_003061429.1 2219824..2222379(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MAKANISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFNSPFVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAAVAETNHYIRPQFN
DNHVIKIQEGRHAVVEKVMGVQEYIPNSISFNQETSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTMFATHYHEL
TELSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPEALLSRADEVLTRLEAQAQSAEIISVPSKV
EPSSAAREGQLSLFPDEDKSQEIIHTLEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=762550 OPT59_RS10965 WP_003061429.1 2219824..2222379(-) (hexA) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGGCAAAAGCTAACATTTCTCCTGGGATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
CAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAGGCAGCGCAACTTTTAGAGATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGAGTGCCACATCATTCTGCCCAGCAATACATTGATGTGTTAATT
GAGTTGGGTTATAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTGTCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGTCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCC
TTGGTTCACTATGAAATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTCTAGATTTGGTAGAGAATGCTAG
AACGAATAAAAAACATGGGAGTCTGTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACAGATTTAAGCAATAGCTTAAAAGGTGTTTACGATATCGAACGCTTATCTAGCCGTGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTAATA
GTCCTTTTGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGCAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGAATTCAAATCTTAGCTTAGTTCCCGACCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAGCGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGCCGTTGCCGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTAAAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTAACCAAGAGACAAGCATTCAATTGATTACAGGTCCAAATATGAGCGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCTCAGATGGGCTCATTTGTAGCTGCTGACCATGTTGATTTGCCTCTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGAGCCAGTGACAATTCCCTTATTCTATTTGATGAACTAGGGAGGGGTACGGCAACTTATGATGGTATGG
CACTGGCTCAGGCAATTATCGAATATATCCATGATAGAGTTGGTGCTAAGACCATGTTTGCAACGCACTATCATGAGTTG
ACAGAATTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTAACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTAGCAAAAATAGCAGGACTTCCTGAGGCCCTGC
TAAGCAGAGCAGATGAGGTGCTTACGCGTTTAGAAGCGCAAGCACAATCTGCTGAGATAATATCAGTCCCTTCAAAAGTT
GAGCCAAGCAGCGCTGCTAGAGAGGGACAGTTATCGCTGTTTCCTGATGAGGATAAGTCTCAGGAGATTATTCACACGTT
AGAAGCTATTGATGTGATGAACATGACTCCACTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.093	100	0.711
mutS	Pseudomonas stutzeri strain ATCC 17587	36.959	100	0.371