Detailed information NTG0762357

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: OPT60_RS00810
• Genome accession: NZ_CP125359
• Coordinates: 129699..130139 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain UT_10236
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 124699..135139

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OPT60_RS00780 (OPT60_00780)	-	126380..126745 (+)	366	WP_003055257.1	DUF1033 family protein	-
OPT60_RS00785 (OPT60_00785)	comGA/cglA	126826..127767 (+)	942	WP_014611930.1	competence type IV pilus ATPase ComGA	Machinery gene
OPT60_RS00790 (OPT60_00790)	comGB	127703..128734 (+)	1032	WP_084916952.1	competence type IV pilus assembly protein ComGB	Machinery gene
OPT60_RS00795 (OPT60_00795)	comGC	128736..129062 (+)	327	WP_084916953.1	competence type IV pilus major pilin ComGC	Machinery gene
OPT60_RS00800 (OPT60_00800)	comGD	129037..129465 (+)	429	WP_257638821.1	competence type IV pilus minor pilin ComGD	Machinery gene
OPT60_RS00805 (OPT60_00805)	comGE	129473..129718 (+)	246	WP_049519695.1	competence type IV pilus minor pilin ComGE	Machinery gene
OPT60_RS00810 (OPT60_00810)	comGF	129699..130139 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
OPT60_RS00815 (OPT60_00815)	comGG	130168..130491 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
OPT60_RS00820 (OPT60_00820)	comGH	130554..131507 (+)	954	WP_003060701.1	class I SAM-dependent methyltransferase	Machinery gene
OPT60_RS00825 (OPT60_00825)	-	131566..132762 (+)	1197	WP_084916957.1	acetate kinase	-
OPT60_RS00830 (OPT60_00830)	-	133069..133275 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
OPT60_RS00835 (OPT60_00835)	-	133378..134058 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
OPT60_RS00840 (OPT60_00840)	-	134076..134513 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=762357 OPT60_RS00810 WP_003061780.1 129699..130139(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain UT_10236]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=762357 OPT60_RS00810 WP_003061780.1 129699..130139(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain UT_10236]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411