Detailed information NTG0762287

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: OQG81_RS03095
• Genome accession: NZ_CP113440
• Coordinates: 554721..555806 (+)
• Length: 361 a.a.
• NCBI ID: WP_014294114.1
• Uniprot ID: A0A380K6B4
• Organism: Streptococcus macedonicus strain E37
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 549721..560806

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OQG81_RS03065 (OQG81_03065)	-	550069..551284 (+)	1216	Protein_541	MFS transporter	-
OQG81_RS03070 (OQG81_03070)	asnA	551657..552649 (+)	993	WP_115266007.1	aspartate--ammonia ligase	-
OQG81_RS03075 (OQG81_03075)	-	552783..553541 (-)	759	Protein_543	hypothetical protein	-
OQG81_RS03085 (OQG81_03085)	rsmD	553674..554213 (+)	540	WP_039670565.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
OQG81_RS03090 (OQG81_03090)	coaD	554246..554743 (+)	498	WP_014294113.1	pantetheine-phosphate adenylyltransferase	-
OQG81_RS03095 (OQG81_03095)	sepM	554721..555806 (+)	1086	WP_014294114.1	SepM family pheromone-processing serine protease	Regulator
OQG81_RS03100 (OQG81_03100)	-	555935..556189 (+)	255	WP_014294115.1	DUF3923 family protein	-
OQG81_RS03105 (OQG81_03105)	-	556259..556750 (-)	492	WP_014294116.1	helix-turn-helix domain-containing protein	-
OQG81_RS03110 (OQG81_03110)	-	556826..557495 (+)	670	Protein_549	MIP/aquaporin family protein	-
OQG81_RS03115 (OQG81_03115)	-	557634..558143 (+)	510	WP_014294119.1	hypothetical protein	-
OQG81_RS03120 (OQG81_03120)	-	558256..559581 (+)	1326	WP_014294120.1	bifunctional metallophosphatase/5'-nucleotidase	-
OQG81_RS03125 (OQG81_03125)	-	559613..560191 (+)	579	WP_014294121.1	YutD family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39123.86 Da
• Isoelectric Point: 4.1372

>NTDB_id=762287 OQG81_RS03095 WP_014294114.1 554721..555806(+) (sepM) [Streptococcus macedonicus strain E37]
MAILKRFKEILKKLGRILYRFKWWILGVVGIAFLLFSLLYPLDYYIEMPGGVYDIRSVLTVDNKEDDEDGSYNFVAVKVS
QATLAQLVYAWLTPYTEISTAADVTGGYSNADYLRINEYYMETSQNTATYQALTLAGKEATLDYQGVYVLNVSDNSTFKG
ILNIADTVTGVNGQTFNSSAELMAYVADLDLGSEVTVQYTSDGEAKEATGKIIELSNGKNGIGIGLVDHTSVSSDVDVDF
HTSGVGGPSAGLMFTLDIYDQLNGEDLRKGRKIAGTGTIESDGSVGDIGGAALKVVAAAKAGADIFFVPNNPVDEETLKK
DPDAKTNYEEAVEAAKDLDTDMKIVPVTTVQEAIDYLRNND

Nucleotide

• Length: 1086 bp

>NTDB_id=762287 OQG81_RS03095 WP_014294114.1 554721..555806(+) (sepM) [Streptococcus macedonicus strain E37]
ATGGCAATCTTAAAAAGATTTAAAGAGATTTTGAAAAAGTTGGGTCGTATTTTATATCGCTTTAAGTGGTGGATATTAGG
TGTTGTAGGCATTGCTTTCTTACTATTTAGCTTGTTGTATCCGCTTGATTACTATATTGAAATGCCTGGTGGTGTTTATG
ATATTCGTAGCGTTTTAACAGTTGATAATAAGGAAGATGATGAAGATGGCTCTTATAATTTTGTGGCTGTCAAGGTTAGT
CAGGCGACCTTGGCACAATTGGTTTATGCTTGGTTAACTCCCTACACAGAAATTTCGACAGCCGCAGATGTGACTGGTGG
TTATAGCAATGCTGATTATCTTCGTATCAATGAGTATTACATGGAAACCTCTCAAAATACAGCGACTTATCAAGCCTTAA
CCTTGGCAGGAAAGGAAGCGACGCTTGATTATCAAGGGGTTTATGTTTTAAATGTTAGTGATAATTCGACGTTTAAAGGG
ATTTTGAATATCGCTGATACGGTAACTGGGGTTAATGGTCAGACATTTAACAGTTCGGCAGAATTAATGGCCTATGTGGC
TGATTTGGATTTAGGGTCTGAGGTAACAGTTCAATATACATCAGACGGCGAAGCAAAAGAAGCCACAGGGAAAATTATTG
AATTGTCAAATGGAAAAAATGGTATCGGAATCGGTTTGGTAGATCATACGTCGGTGTCATCAGATGTTGATGTTGATTTT
CATACGAGTGGTGTCGGTGGTCCAAGTGCTGGTTTGATGTTTACGCTTGATATTTATGACCAATTAAATGGTGAAGATTT
GCGTAAAGGTCGTAAAATTGCTGGTACAGGTACGATTGAATCAGATGGTTCAGTCGGGGATATTGGTGGCGCAGCACTCA
AAGTTGTTGCTGCTGCTAAAGCTGGTGCGGATATTTTCTTTGTTCCAAATAACCCTGTGGATGAGGAAACATTGAAAAAA
GATCCTGATGCGAAAACGAACTATGAAGAAGCTGTCGAAGCTGCTAAAGACCTCGATACCGATATGAAAATCGTCCCAGT
CACAACGGTCCAAGAAGCAATTGACTATCTACGAAACAATGATTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (246-323)

• PDZ domain (PDZ_2) (145-209)

3D structure

• AlphaFold DB: A0A380K6B4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	67.742	94.46	0.64