Detailed information NTG0762244

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: OXA86_RS09475
• Genome accession: NZ_CP113439
• Coordinates: 2087057..2089789 (+)
• Length: 910 a.a.
• NCBI ID: WP_014841967.1
• Uniprot ID: A0AAV2V0G3
• Organism: Legionella pneumophila strain PATHC002
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2082057..2094789

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OXA86_RS09450 (OXA86_09450)	-	2083026..2084288 (-)	1263	WP_014841965.1	serine hydrolase domain-containing protein	-
OXA86_RS09455 (OXA86_09455)	-	2084455..2084748 (-)	294	WP_014841366.1	GIY-YIG nuclease family protein	-
OXA86_RS09460 (OXA86_09460)	-	2084774..2085233 (-)	460	Protein_1855	hypothetical protein	-
OXA86_RS09465 (OXA86_09465)	-	2085244..2085486 (+)	243	WP_268188030.1	hypothetical protein	-
OXA86_RS09470 (OXA86_09470)	gltX	2085546..2086958 (-)	1413	WP_014841966.1	glutamate--tRNA ligase	-
OXA86_RS09475 (OXA86_09475)	letS	2087057..2089789 (+)	2733	WP_014841967.1	two-component system sensor histidine kinase LetS	Regulator
OXA86_RS09480 (OXA86_09480)	-	2089887..2091131 (+)	1245	WP_011214166.1	6-phosphofructokinase	-
OXA86_RS09485 (OXA86_09485)	pilA2	2091128..2091541 (-)	414	WP_013101573.1	pilin	Machinery gene
OXA86_RS09490 (OXA86_09490)	pilA2	2091739..2092149 (-)	411	WP_011214168.1	pilin	Machinery gene
OXA86_RS09495 (OXA86_09495)	-	2092452..2092769 (+)	318	WP_014841968.1	BolA family protein	-
OXA86_RS09500 (OXA86_09500)	-	2092844..2094265 (+)	1422	WP_014841969.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102974.40 Da
• Isoelectric Point: 7.5329

>NTDB_id=762244 OXA86_RS09475 WP_014841967.1 2087057..2089789(+) (letS) [Legionella pneumophila strain PATHC002]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKEPSTPKIFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDVRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAIGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPEILIAEDNPVNKMLLTSLLNNNANITTVDDGEMAVTACEDKKFD
MILLDLHMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKSGVDFCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNRDEFIELMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=762244 OXA86_RS09475 WP_014841967.1 2087057..2089789(+) (letS) [Legionella pneumophila strain PATHC002]
ATGTTGAAAAGTATTGGTATTAAATATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTCGCCTTGCTTTTTGC
TTTTTTTTATAACGGCCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTATATTAGGCAATTAC
TTCCAGCAGCCCAGTATGCCATGCTTCGTAATGATTACCGTACATTGCAGGGTTTAATCAATGCCTCAACCATTAACCCG
GAGGTAAAAGCTTTGGCATTTTATAATGCTGATGGTCGATTAATTGCTTATCGTGGTGGCAAGCACTCTATTCATAAACC
ATTCAATCCACCTGACTATACAGGTGACTACATTGAAAGTAAGCAAATTAACCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGCACAGAATTCAAAGAGCCTTCTACGCCTAAAATATTCCAGGCTGACGAT
ATATTAGGCTGGTTATCCATTGACATTGATACACAATCACTACTTATAAAACGCTATCAAATGCTCATCGTTACCATTTT
TATTACTCTATTCGGTTTACTGATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTCGAAGTATGAAGCAAATTTTAAGCAATGAATTTGAAACTGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTACAACGACAATATTTAAATACAGTTCGTGATTTGAATCACCACATTGAAATCGCCAC
CGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCACTGGAAAAGAAAAAAACTGAAGAAA
AAAGTCGACAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATTCGCACCCCAATGAATGGCGTGATTGGTTTTACA
AATGTTTTATTGGAAAGCAAGCTGGACCCTTTACAACTGGACTACGTTAAAACGATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTTGATTGCATCCCGCTAGACGTAA
GAGGTTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATCGATTTAATTCCGATTACAGAC
ATCAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAACAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGATCATGGATACGTTCTTATACGTACTAAAATCGAGCAAGAAACAGATAAGGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTTAATCAGGCAGACACCAGCATC
ACACGCCGTTACGGTGGCTCAGGATTAGGCTTGGTTATATGTAAAAAGCTATGTGAAGAAATGCATGGACGTATTAGTCT
AACCAGTGAAATCAACAAAGGCTCTACTTTTAGTGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCGCATTTAAAAATCATTTGCTTTGATGACAATCCCCTCCATTTGGAAGCAATAGGTAATGGC
TTGGGATTTTGGGGTATAGAGGCTATACGCGTTGACTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAACGTCAATCAAGGATGTGAGCGACAAGCCGCTGAACTCATTGCCAAACATAAGCAAATCCCTT
TTGTGTTAATTTCCAAATGGCCTATTAATGACTTTGCAGCGCTTGGTGCCAGGGGTTTTCTTTACAAACCTATTAGTATC
CAAAAGCTTCAGGATCTGATTGAATCGATAGCCAATGAAAACCAAACCGAGAAAAATACGAACCAGGAACTGGATACTTT
ACGCGAACAGCTTCGTTTTCTTCATCCAGAGATACTGATTGCAGAAGACAACCCTGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACAACGGTTGACGATGGCGAAATGGCCGTTACTGCTTGTGAGGATAAAAAATTTGAT
ATGATTTTACTGGATCTGCATATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGTCAAAAATCCCTAATGAA
TAAACACTCCCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATCCGGAGTTGATT
TTTGTTTTCAAAAACCTATAGATGAAAAGCAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATCGATTGGCAATTATGCGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTCATAGAAGA
ATTATATAAGAATCGTGACGAGTTTATTGAGTTAATGCATCAAAAAAACGTAAAGGGCCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGCGTACCTATTTTACAAAAGAGAGTAGCTCAACTAGAGAAGCTTGCAAGACGAACA
GCTAATGCTGATAATTTAACCGAAGCCTTTACCGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCACAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Response regulator receiver domain (Response_reg) (678-787)

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-899)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	99.341	100	0.993