Detailed information NTG0762232

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: OXA86_RS05670
• Genome accession: NZ_CP113439
• Coordinates: 1264232..1265560 (+)
• Length: 442 a.a.
• NCBI ID: WP_014841410.1
• Uniprot ID: A0AAV2UW00
• Organism: Legionella pneumophila strain PATHC002
• Function: regulate pilin expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1262212..1263299	1264232..1265560	flank	933

Gene organization within MGE regions

Location: 1262212..1265560

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OXA86_RS05665 (OXA86_05665)	-	1263474..1264235 (+)	762	WP_268188203.1	sensor histidine kinase	-
OXA86_RS05670 (OXA86_05670)	pilR	1264232..1265560 (+)	1329	WP_014841410.1	sigma-54-dependent transcriptional regulator	Regulator

Sequence

Protein

• Length: 442 a.a.
• Molecular weight: 49150.14 Da
• Isoelectric Point: 7.1405

>NTDB_id=762232 OXA86_RS05670 WP_014841410.1 1264232..1265560(+) (pilR) [Legionella pneumophila strain PATHC002]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQVPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEGLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSANLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide

• Length: 1329 bp

>NTDB_id=762232 OXA86_RS05670 WP_014841410.1 1264232..1265560(+) (pilR) [Legionella pneumophila strain PATHC002]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGGTGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGGTCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGAAAAGAATTGGTCGCTCAGTTGATCCATGCTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCTATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGCGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAGTTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCTATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTACATTTGCCAAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAGCTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCTGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (399-439)

• Sigma-54 interaction domain (Sigma54_activat) (134-300)

• Response regulator receiver domain (Response_reg) (6-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	59.326	100	0.597
pilR	Acinetobacter baumannii strain A118	48.584	100	0.505