Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   OXA91_RS05925 Genome accession   NZ_CP113438
Coordinates   1322089..1323417 (+) Length   442 a.a.
NCBI ID   WP_010946908.1    Uniprot ID   Q5ZWB1
Organism   Legionella pneumophila strain PATHC003     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1317089..1328417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OXA91_RS05905 (OXA91_05905) amrS 1317220..1318296 (+) 1077 WP_015444592.1 AmmeMemoRadiSam system radical SAM enzyme -
  OXA91_RS05910 (OXA91_05910) - 1318355..1318774 (+) 420 WP_010946905.1 lpg1171 family Dot/Icm T4SS effector -
  OXA91_RS05915 (OXA91_05915) lidL 1318923..1320410 (+) 1488 WP_010946906.1 Dot/Icm type IV secretion system effector LidL -
  OXA91_RS05920 (OXA91_05920) - 1320506..1322092 (+) 1587 WP_010946907.1 sensor histidine kinase -
  OXA91_RS05925 (OXA91_05925) pilR 1322089..1323417 (+) 1329 WP_010946908.1 sigma-54-dependent transcriptional regulator Regulator
  OXA91_RS05930 (OXA91_05930) - 1323844..1324089 (+) 246 WP_011213531.1 hypothetical protein -
  OXA91_RS05935 (OXA91_05935) - 1324528..1325463 (-) 936 WP_010946909.1 alpha/beta fold hydrolase -
  OXA91_RS05940 (OXA91_05940) - 1325742..1327178 (-) 1437 WP_015444590.1 M48 family metalloprotease -
  OXA91_RS05945 (OXA91_05945) ribD 1327241..1328314 (+) 1074 WP_010946911.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49283.32 Da        Isoelectric Point: 6.9043

>NTDB_id=762190 OXA91_RS05925 WP_010946908.1 1322089..1323417(+) (pilR) [Legionella pneumophila strain PATHC003]
MIKSKVLVIDDEPDIRELLTLTLSRMGLICDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQLPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPVDLKMLRELVKTALSMQNPSTESPDEGLLVGESLIMQQLRESIHKLARSQAPVFI
QGDSGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEIPVDVRILSASHKNLIEEINAGRFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
KKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=762190 OXA91_RS05925 WP_010946908.1 1322089..1323417(+) (pilR) [Legionella pneumophila strain PATHC003]
ATGATCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGACATTAGAGAGTTATTAACTCTTACTTTATCACGCATGGG
TTTAATTTGTGATGCGGTGTCTGATTTTAAGCAGGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTGCCTGACGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCACAGTTGCCAGTCGCTGTC
ATTACTGCTTATGGAAATGTAGAAGGTGCGGTCAATACTTTAAAGGCTGGTGCATTTGATTATGTATCCAAGCCTGTTGA
CTTAAAGATGCTCAGAGAACTCGTTAAGACGGCATTATCCATGCAAAATCCGTCTACCGAGAGTCCTGATGAAGGTCTAT
TGGTTGGTGAGAGCCTGATAATGCAACAACTGCGTGAGAGCATTCATAAATTAGCTCGTAGTCAGGCACCGGTTTTCATT
CAAGGTGATTCGGGTGTTGGGAAAGAACTTGTTGCTCAGCTGATCCATGCTAATGGTCCCAGAAAAGATAAGCCATTTAT
TCCTGTAAATTGTGGTGCCATACCTGGTGAGTTGATGGAGTCAGAGTTTTTTGGCCATAAAAAAGGAAGTTTTACAGGAG
CGATTTCGGATAAAACAGGATTATTTGTTGCAGCTCATGGCGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTTAAATTACTACGCGCAATTCAGGAGAAGGCAATTAAACCAATAGGTGAGTTATATGAAATTCCGGTCGA
TGTTCGCATTCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAATCAATGCAGGGAGGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAGCTGCGTGTTCCAACTTTAATGGAAAGGCTTTCTGATATCCCTTGCCTGACAGAGGCGATATTA
AAAAAATTATCTAAAAATCAAAACAGAAATTTGGTTAAAATAAATCCCTCTTGTTTTGAAATATTGAGCCGTTATCATTT
CCCGGGAAATGTCAGAGAGTTGGAAAATATCCTTGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTCATAGAGCCAAGCG
ATTTACATTTGCCCAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACGTCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTTGAGAAAACAAAATGGAACAGAACCGCTGCGGCACAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGACTTGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZWB1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.865

100

0.604
  pilR Acinetobacter baumannii strain A118

48.802

100

0.507