Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   QMA14_RS06410 Genome accession   NZ_CP125087
Coordinates   1297509..1299335 (+) Length   608 a.a.
NCBI ID   WP_284173578.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain EL1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1292509..1304335
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QMA14_RS06390 (QMA14_06390) msbA 1293753..1295501 (+) 1749 WP_005697209.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  QMA14_RS06395 (QMA14_06395) lpxK 1295555..1296535 (+) 981 WP_284173575.1 tetraacyldisaccharide 4'-kinase -
  QMA14_RS06400 (QMA14_06400) - 1296552..1296731 (+) 180 WP_284173576.1 Trm112 family protein -
  QMA14_RS06405 (QMA14_06405) kdsB 1296741..1297499 (+) 759 WP_284173577.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  QMA14_RS06410 (QMA14_06410) uvrC 1297509..1299335 (+) 1827 WP_284173578.1 excinuclease ABC subunit UvrC Machinery gene
  QMA14_RS06415 (QMA14_06415) - 1299406..1300125 (+) 720 WP_005696420.1 TerC family protein -
  QMA14_RS06420 (QMA14_06420) - 1300163..1301215 (-) 1053 WP_005696419.1 ABC transporter ATP-binding protein -
  QMA14_RS06425 (QMA14_06425) - 1301228..1302748 (-) 1521 WP_005696417.1 iron ABC transporter permease -
  QMA14_RS06430 (QMA14_06430) - 1302846..1303844 (-) 999 WP_284173579.1 iron ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 69256.06 Da        Isoelectric Point: 8.7399

>NTDB_id=761814 QMA14_RS06410 WP_284173578.1 1297509..1299335(+) (uvrC) [Haemophilus parainfluenzae strain EL1]
MFDSKKFLSDVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVSSIHHIDTTITSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGTKKITGEYFGPYPHAGAVRETLSLMQKLFPVRQCENSVYNNRS
RPCLQYQIGRCCAPCVPGYVTDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRDLDFEGAARYRDQIQAVRAVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTATFVGQFYLQGHQGRSIPNSIIVDHK
LDEKNELEALLTEQAGRKVVIQESAKGDKGKYLQLAQINAKAALATQLKQSSRMHERYQALCELLDMPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALKKRYDRDLDEDKIPDIIFIDGGKGQLNRALEVFHHL
NVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRQKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKNATLDEIASVPGISKALAEKIFETLKS

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=761814 QMA14_RS06410 WP_284173578.1 1297509..1299335(+) (uvrC) [Haemophilus parainfluenzae strain EL1]
ATGTTTGATTCCAAGAAGTTTCTCTCTGACGTTTCTCATGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTGGGCAAAGCGAAAGATCTCAAAAAGCGACTTTCCAGCTATTTCCGCAAAAACTTAAGCAGCAAAAAAACAG
AAGCCTTGGTGTCGTCAATTCATCATATTGATACGACGATTACTTCTTCTGAAACAGAAGCGTTATTGCTTGAGCATAAT
TTCATTAAGCTTTATCAACCTCGTTATAACGTATTATTGCGAGATGATAAATCCTATCCTTTTATTTTATTGACGAAAGA
ACGTCATCCTCGTATTACTTCTTATCGCGGAACGAAAAAAATTACAGGTGAGTATTTCGGGCCTTATCCTCATGCAGGTG
CAGTGCGTGAAACCTTGTCGTTAATGCAAAAATTATTCCCTGTTCGTCAATGTGAAAATTCGGTTTATAACAATCGTTCC
CGCCCTTGTTTGCAATATCAAATCGGGCGTTGTTGTGCACCTTGTGTGCCAGGTTATGTGACTGATGAGGAATATAACCA
ACAAGTTGAATTAGCTCGATTATTTTTGCAAGGGAAAGATCAGCAAGTATTAGATTACCTCATCGGCAAAATGGAACAGG
CGAGCCGAGACTTAGATTTTGAAGGTGCGGCGCGTTATCGAGATCAAATTCAAGCGGTTCGCGCGGTTATCGAAAAACAA
TTTGTATCCAATGAGCGTTTGGACGACATGGATATTATGTCTATTGCGTATCAGCACGGTTTAGCTTGTGTTCAAGTGAT
GTTTATTCGTCAAGGTAAAGTATTAGGCAATCGCAGTTATTTTCCTAAAGTACCCGCTAACACTGATTTATCCGAACTCA
CAGCAACGTTTGTTGGGCAGTTTTATTTGCAAGGTCATCAGGGCAGAAGTATTCCTAATAGTATTATTGTGGATCATAAA
CTAGATGAAAAAAATGAGCTTGAGGCCTTGTTAACTGAACAAGCTGGCCGAAAAGTGGTGATACAAGAATCCGCTAAAGG
CGATAAAGGTAAATATCTGCAACTAGCACAAATTAATGCCAAAGCGGCGTTAGCGACTCAACTTAAACAATCTTCCCGAA
TGCACGAACGTTATCAAGCCCTTTGCGAATTGCTTGATATGCCTGAAATTAAACGTATGGAATGTTTTGATATTAGTCAT
ACGATGGGGAATCAAACTGTAGCATCTTGCGTGGTATTTAATCAAGAAGGCCCACTGAAATCAGATTATCGTCGTTTTAA
TATTGAAGGCATTACCGGTGGTGATGACTATGCCGCGATGGAGCAAGCCTTAAAGAAACGTTACGATCGTGATCTTGATG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGTAAAGGACAGCTTAATCGCGCCTTAGAGGTTTTTCATCATCTC
AACGTAAAATGGGATAAAAATCGACCGCACTTAATCGGTGTGGCAAAAGGTGTGGATCGTCGAGCAGGACAAGAAGTGTT
GATTATCAGCAAACAAGATCGTGAGATTCACTTGCCGGATGATAGCCTTGCGCTGCATTTAATCCAACATATTCGAGATG
AAAGCCATAATCATGCGATTAGCGGACATCGTCAAAAACGTCAAAAAGCCTTTACCCAAAGTGGCTTAGAAACCATTGAA
GGGGTAGGCGCCAAACGACGCCAAGCCTTGTTGAAATATTTAGGTGGATTACAAGGTGTCAAAAATGCCACATTGGATGA
AATCGCCTCAGTGCCCGGTATTTCTAAAGCCTTAGCAGAAAAGATTTTCGAGACCTTAAAAAGTTAG

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

UvrB/uvrC motif (UVR)

(210-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.793

98.355

0.372
  uvrC Streptococcus pneumoniae R6

37.647

97.862

0.368
  uvrC Streptococcus pneumoniae D39

37.647

97.862

0.368