Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OTB22_RS08660 Genome accession   NZ_CP113267
Coordinates   1706544..1707233 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1701544..1712233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS11215 - 1702218..1702547 (-) 330 WP_281057006.1 transposase -
  OTB22_RS11110 - 1703158..1704033 (+) 876 Protein_1719 lanthionine synthetase LanC family protein -
  OTB22_RS08650 (OTB22_08655) - 1704076..1705308 (+) 1233 WP_000765691.1 MFS transporter -
  OTB22_RS08655 (OTB22_08660) cbpC 1705426..1706445 (-) 1020 WP_268217905.1 choline-binding protein CbpC -
  OTB22_RS08660 (OTB22_08665) covR 1706544..1707233 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  OTB22_RS08665 (OTB22_08670) gndA 1707245..1708669 (-) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  OTB22_RS08670 (OTB22_08675) mapZ 1708745..1710139 (-) 1395 WP_023396578.1 cell division site-positioning protein MapZ -
  OTB22_RS08675 (OTB22_08680) - 1710152..1711309 (-) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  OTB22_RS08685 (OTB22_08690) gpsB 1711795..1712124 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=761491 OTB22_RS08660 WP_000518011.1 1706544..1707233(-) (covR) [Streptococcus pneumoniae strain BC2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=761491 OTB22_RS08660 WP_000518011.1 1706544..1707233(-) (covR) [Streptococcus pneumoniae strain BC2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467