Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   OTB22_RS06500 Genome accession   NZ_CP113267
Coordinates   1278884..1280116 (-) Length   410 a.a.
NCBI ID   WP_000106346.1    Uniprot ID   A0A064C077
Organism   Streptococcus pneumoniae strain BC2     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1273884..1285116
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OTB22_RS06470 (OTB22_06475) - 1274071..1275039 (+) 969 WP_000081002.1 NAD(P)/FAD-dependent oxidoreductase -
  OTB22_RS06475 (OTB22_06480) whiA 1275073..1275984 (-) 912 WP_000011303.1 DNA-binding protein WhiA -
  OTB22_RS06480 (OTB22_06485) - 1275981..1276958 (-) 978 WP_001231086.1 YvcK family protein -
  OTB22_RS06485 (OTB22_06490) rapZ 1276955..1277845 (-) 891 WP_000163035.1 RNase adapter RapZ -
  OTB22_RS06490 (OTB22_06495) - 1277897..1278277 (-) 381 WP_001140413.1 RidA family protein -
  OTB22_RS06495 (OTB22_06500) yihA 1278288..1278875 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  OTB22_RS06500 (OTB22_06505) clpX 1278884..1280116 (-) 1233 WP_000106346.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  OTB22_RS06505 (OTB22_06510) - 1280148..1280318 (-) 171 WP_000442275.1 hypothetical protein -
  OTB22_RS06510 (OTB22_06515) - 1280318..1280824 (-) 507 WP_000162484.1 dihydrofolate reductase -
  OTB22_RS06515 (OTB22_06520) - 1280954..1281472 (-) 519 WP_061364495.1 Dps family protein -
  OTB22_RS06520 (OTB22_06525) - 1281902..1283184 (+) 1283 Protein_1297 transposase -
  OTB22_RS06525 (OTB22_06530) rpsA 1283269..1284471 (-) 1203 WP_001001623.1 30S ribosomal protein S1 -
  OTB22_RS06540 (OTB22_06545) - 1284844..1285074 (-) 231 WP_000037113.1 DUF2969 domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45798.35 Da        Isoelectric Point: 4.4550

>NTDB_id=761479 OTB22_RS06500 WP_000106346.1 1278884..1280116(-) (clpX) [Streptococcus pneumoniae strain BC2]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=761479 OTB22_RS06500 WP_000106346.1 1278884..1280116(-) (clpX) [Streptococcus pneumoniae strain BC2]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A064C077

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.585

100

0.866
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561