Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   OS912_RS08230 Genome accession   NZ_CP113266
Coordinates   1605760..1606449 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain BC1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1600760..1611449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS08205 (OS912_08210) gpsB 1600893..1601222 (+) 330 WP_061816987.1 cell division regulator GpsB -
  OS912_RS08215 (OS912_08220) - 1601708..1602865 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  OS912_RS08220 (OS912_08225) mapZ 1602878..1604248 (+) 1371 WP_268232889.1 cell division site-positioning protein MapZ -
  OS912_RS08225 (OS912_08230) gndA 1604324..1605748 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  OS912_RS08230 (OS912_08235) covR 1605760..1606449 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  OS912_RS08235 (OS912_08240) cbpJ 1606548..1607546 (+) 999 WP_268232890.1 choline-binding protein CbpJ -
  OS912_RS08240 (OS912_08245) - 1607665..1608897 (-) 1233 WP_050213803.1 MFS transporter -
  OS912_RS08245 (OS912_08250) - 1608940..1609815 (-) 876 WP_235800344.1 lanthionine synthetase LanC family protein -
  OS912_RS11070 - 1610427..1610756 (+) 330 WP_000196981.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=761440 OS912_RS08230 WP_000518008.1 1605760..1606449(+) (covR) [Streptococcus pneumoniae strain BC1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=761440 OS912_RS08230 WP_000518008.1 1605760..1606449(+) (covR) [Streptococcus pneumoniae strain BC1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467